cytotoxicity, immunologic

Bispecific immune cell engager enhances the anticancer activity of CD16+ NK cells and macrophages in vitro, and eliminates cancer metastasis in NK humanized NOG mice
Shahryar Khoshtinat Nikkhoi, Ge Yang, Hajar Owji, Mayara Grizotte-Lake, Rick I Cohen, Lazaro Gil Gonzalez, Mohammad Massumi, Arash Hatefi

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008295; DOI: 10.1136/jitc-2023-008295
Cancer-oocyte SAS1B protein is expressed at the cell surface of multiple solid tumors and targeted with antibody-drug conjugates
Arabinda Mandal, Jagathpala Shetty, Christine A Tran, Walter C Olson, Mriganka Mandal, Bhupal Ban, Eusebio S Pires, Sara J Adair, Todd W Bauer, Craig L Slingluff, John C Herr

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008430; DOI: 10.1136/jitc-2023-008430
Anti-BCMA CAR-T cells therapy for a patient with extremely high membrane BCMA expression: a case report
Dan Li, Yimei Que, Shengnan Ding, Guang Hu, Wen Wang, Xia Mao, Ying Wang, Chunrui Li, Liang Huang, Jianfeng Zhou, Wei Zhang, Min Xiao

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005403; DOI: 10.1136/jitc-2022-005403
COLAR: open-label clinical study of IL-6 blockade with tocilizumab for the treatment of immune checkpoint inhibitor-induced colitis and arthritis
Rikke Boedker Holmstroem, Ole Haagen Nielsen, Søren Jacobsen, Lene Buhl Riis, Susann Theile, Jacob Tveiten Bjerrum, Peter Vilmann, Julia Sidenius Johansen, Mogens Karsbøl Boisen, Rikke Helene Løvendahl Eefsen, Inge Marie Svane, Dorte Lisbet Nielsen, Inna Markovna Chen

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005111; DOI: 10.1136/jitc-2022-005111
Cardiovascular toxicities associated with bispecific T-cell engager therapy
Ahmed Sayed, Malak Munir, Sanam M Ghazi, Mussammat Ferdousi, Satyam Krishan, Adnan Shaaban, Alma Habib, Onaopepo Kola-Kehinde, Patrick Ruz, Sarah Khan, Sneha Sharma, Alexa Meara, Syed Mahmood, Stephanie Feldman, Eric H Yang, Jiwon Kim, Narendranath Epperla, Daniel Addison

Journal for ImmunoTherapy of Cancer Feb 2024, 12 (2) e008518; DOI: 10.1136/jitc-2023-008518
CLN-978, a novel half-life extended CD19/CD3/HSA-specific T cell-engaging antibody construct with potent activity against B-cell malignancies with low CD19 expression
Kristan Meetze, Naveen K Mehta, Bochong Li, Hannah M Findlay, Timothy B London, Agapitos Patakas, Jennifer S Michaelson, Patrick A Baeuerle

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007398; DOI: 10.1136/jitc-2023-007398
Id-neoantigen vaccine induces therapeutic CD8⁺ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
Marita Westhrin, Jana Blazevski, Ana Textor, Pegah Abdollahi, Ramakrishna Prabhu Gopalakrishnan, Linda Thuy Ngo, Peter Olaf Hofgaard, Julia Heinzelbecker, Sonja Bobic, Even Fossum, Heidi Cecilie Larsen Spång, Ranveig Braathen, Bjarne Bogen

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e006944; DOI: 10.1136/jitc-2023-006944
Impact of prior therapies and subsequent transplantation on outcomes in adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with brexucabtagene autoleucel in ZUMA-3
Bijal D Shah, Ryan D Cassaday, Jae H Park, Roch Houot, Olalekan O Oluwole, Aaron C Logan, Nicolas Boissel, Thibaut Leguay, Michael R Bishop, Max S Topp, Dimitrios Tzachanis, Kristen M O'Dwyer, Martha L Arellano, Yi Lin, Maria R Baer, Gary J Schiller, Marion Subklewe, Mehrdad Abedi, Monique C Minnema, William G Wierda, Daniel J DeAngelo, Patrick J Stiff, Deepa Jeyakumar, Daqin Mao, Sabina Adhikary, Lang Zhou, Petra C Schuberth, Rita Damico Khalid, Armin Ghobadia

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007118; DOI: 10.1136/jitc-2023-007118
Cancer cells resist antibody-mediated destruction by neutrophils through activation of the exocyst complex
Dieke J van Rees, Panagiota Bouti, Bart Klein, Paul J H Verkuijlen, Michel van Houdt, Karin Schornagel, Anton T J Tool, David Venet, Christos Sotiriou, Sarra El-Abed, Miguel Izquierdo, Sébastien Guillaume, Cristina Saura, Serena Di Cosimo, Jens Huober, Rebecca Roylance, Sung-Bae Kim, Taco W Kuijpers, Robin van Bruggen, Timo K van den Berg, Hanke L Matlung

Journal for ImmunoTherapy of Cancer Jun 2022, 10 (6) e004820; DOI: 10.1136/jitc-2022-004820
Targeting of Nrf2 improves antitumoral responses by human NK cells, TIL and CAR T cells during oxidative stress
Stefanie Renken, Takahiro Nakajima, Isabelle Magalhaes, Jonas Mattsson, Andreas Lundqvist, Elias S J Arnér, Rolf Kiessling, Stina Linnea Wickström

Journal for ImmunoTherapy of Cancer Jun 2022, 10 (6) e004458; DOI: 10.1136/jitc-2021-004458

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cytotoxicity, immunologic

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