drug evaluation, preclinical

Preclinical investigations and a first-in-human phase I trial of M4112, the first dual inhibitor of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase 2, in patients with advanced solid tumors
Aung Naing, Joseph P Eder, Sarina A Piha-Paul, Claude Gimmi, Elizabeth Hussey, Sen Zhang, Vera Hildebrand, Vinayak Hosagrahara, Christina Habermehl, Jacques Moisan, Kyriakos P Papadopoulos

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000870; DOI: 10.1136/jitc-2020-000870
Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects
Julia Delahousse, Charles Skarbek, Mélanie Desbois, Jean-Luc Perfettini, Nathalie Chaput, Angelo Paci

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000916; DOI: 10.1136/jitc-2020-000916
Immunization associated with primary tumor growth leads to rejection of commonly used syngeneic tumors upon tumor rechallenge
Bruno Alicke, Klara Totpal, Jill M Schartner, Amy M Berkley, Sophie M Lehar, Aude-Hélène Capietto, Rafael A Cubas, Stephen E Gould

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e000532; DOI: 10.1136/jitc-2020-000532
Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies
Lambros Tselikas, Thierry de Baere, Thomas Isoardo, Sandrine Susini, Karine Ser-Le Roux, Mélanie Polrot, Julien Adam, Mathieu Rouanne, Laurence Zitvogel, Laurence Moine, Fréderic Deschamps, Aurélien Marabelle

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000579; DOI: 10.1136/jitc-2020-000579
CD40 agonist-induced IL-12p40 potentiates hepatotoxicity
Caroline Bonnans, Graham Thomas, Wenqian He, Breanna Jung, Wei Chen, Min Liao, Jonathan Heyen, Bernard Buetow, Smitha Pillai, Diane Matsumoto, Javier Chaparro-Riggers, Shahram Salek-Ardakani, Yan Qu

Journal for ImmunoTherapy of Cancer May 2020, 8 (1) e000624; DOI: 10.1136/jitc-2020-000624

Log in using your username and password

Main menu

Log in using your username and password

You are here

drug evaluation, preclinical