gastrointestinal neoplasms

Cytoplasmic-delivery of polyinosine-polycytidylic acid inhibits pancreatic cancer progression increasing survival by activating Stat1-CCL2-mediated immunity
Praveen Bhoopathi, Amit Kumar, Anjan K Pradhan, Santanu Maji, Padmanabhan Mannangatti, Jolene J Windle, Mark A Subler, Dongyu Zhang, Vignesh Vudatha, Jose G Trevino, Esha Madan, Azeddine Atfi, Devanand Sarkar, Rajan Gogna, Swadesh K Das, Luni Emdad, Paul B Fisher

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007624; DOI: 10.1136/jitc-2023-007624
Impact of Helicobacter pylori infection status on outcomes among patients with advanced gastric cancer treated with immune checkpoint inhibitors
Patrick T Magahis, Steven B Maron, Darren Cowzer, Stephanie King, Mark Schattner, Yelena Janjigian, David Faleck, Monika Laszkowska

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007699; DOI: 10.1136/jitc-2023-007699
Complete response to immunotherapy in a patient with high-risk stage III colorectal cancer after ctDNA-guided detection of early adjuvant treatment failure
Nicholas Lucchesi, Jenna M Ally, Matthew J Reilley

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007434; DOI: 10.1136/jitc-2023-007434
Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer
Yibo Quan, Jie He, Qi Zou, Liuxi Zhang, Qihui Sun, Hongli Huang, Wanglin Li, Keping Xie, Fang Wei

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007080; DOI: 10.1136/jitc-2023-007080
Depicting the landscape of gut microbial-metabolic interaction and microbial-host immune heterogeneity in deficient and proficient DNA mismatch repair colorectal cancers
Jinming Li, Yangyang Guo, Jianqiang Liu, Fanying Guo, Lutao Du, Yongzhi Yang, Xinxiang Li, Yanlei Ma

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007420; DOI: 10.1136/jitc-2023-007420
Association between gene expression signatures and clinical outcomes of pembrolizumab versus paclitaxel in advanced gastric cancer: exploratory analysis from the randomized, controlled, phase III KEYNOTE-061 trial
Kohei Shitara, Maria Di Bartolomeo, Mario Mandala, Min-Hee Ryu, Christian Caglevic, Tomasz Olesinski, Hyun Cheol Chung, Kei Muro, Eray Goekkurt, Raymond S McDermott, Wasat Mansoor, Zev A Wainberg, Chie-Schin Shih, Julie Kobie, Michael Nebozhyn, Razvan Cristescu, Z Alexander Cao, Andrey Loboda, Mustafa Özgüroğlu

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006920; DOI: 10.1136/jitc-2023-006920
Characterization of intratumoral tertiary lymphoid structures in pancreatic ductal adenocarcinoma: cellular properties and prognostic significance
Xuan Zou, Xuan Lin, He Cheng, Yusheng Chen, Ruijie Wang, Mingjian Ma, Yu Liu, Zhengjie Dai, Yesboli Tasiheng, Yu Yan, Qinqin Hou, Fei Ding, Huan Chen, Xianjun Yu, Xu Wang, Chen Liu

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006698; DOI: 10.1136/jitc-2023-006698
G-MDSC-derived exosomes mediate the differentiation of M-MDSC into M2 macrophages promoting colitis-to-cancer transition
Yungang Wang, Hongli Liu, Zhe Zhang, Dezhi Bian, Keke Shao, Shengjun Wang, Yanxia Ding

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006166; DOI: 10.1136/jitc-2022-006166
Associations of subcutaneous fat area and Systemic Immune-inflammation Index with survival in patients with advanced gastric cancer receiving dual PD-1 and HER2 blockade
Meng He, Zi-Fan Chen, Li Zhang, Xiangyu Gao, Xiaoyi Chong, Hao-shen Li, Lin Shen, Jiafu Ji, Xiaotian Zhang, Bin Dong, Zi-Yu Li, Tang Lei

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e007054; DOI: 10.1136/jitc-2023-007054
G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans
Victoire Cardot-Ruffino, Naima Bollenrucher, Luisa Delius, S Jennifer Wang, Lauren K Brais, Joshua Remland, C Elizabeth Keheler, Keri M Sullivan, Thomas A Abrams, Leah H Biller, Peter C Enzinger, Nadine J McCleary, Anuj K Patel, Douglas A Rubinson, Benjamin Schlechter, Sarah Slater, Matthew B Yurgelun, James M Cleary, Kimberly Perez, Michael Dougan, Kimmie Ng, Brian M Wolpin, Harshabad Singh, Stephanie K Dougan

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006589; DOI: 10.1136/jitc-2022-006589

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