gastrointestinal neoplasms

Depicting the landscape of gut microbial-metabolic interaction and microbial-host immune heterogeneity in deficient and proficient DNA mismatch repair colorectal cancers
Jinming Li, Yangyang Guo, Jianqiang Liu, Fanying Guo, Lutao Du, Yongzhi Yang, Xinxiang Li, Yanlei Ma

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007420; DOI: 10.1136/jitc-2023-007420
Association between gene expression signatures and clinical outcomes of pembrolizumab versus paclitaxel in advanced gastric cancer: exploratory analysis from the randomized, controlled, phase III KEYNOTE-061 trial
Kohei Shitara, Maria Di Bartolomeo, Mario Mandala, Min-Hee Ryu, Christian Caglevic, Tomasz Olesinski, Hyun Cheol Chung, Kei Muro, Eray Goekkurt, Raymond S McDermott, Wasat Mansoor, Zev A Wainberg, Chie-Schin Shih, Julie Kobie, Michael Nebozhyn, Razvan Cristescu, Z Alexander Cao, Andrey Loboda, Mustafa Özgüroğlu

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006920; DOI: 10.1136/jitc-2023-006920
Combined inhibition of CXCL12 and PD-1 in MSS colorectal and pancreatic cancer: modulation of the microenvironment and clinical effects
Meggy Suarez-Carmona, Anja Williams, Jutta Schreiber, Nicolas Hohmann, Ulrike Pruefer, Jürgen Krauss, Dirk Jäger, Anna Frömming, Diana Beyer, Dirk Eulberg, Jarf Ulf Jungelius, Matthias Baumann, Aram Mangasarian, Niels Halama

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002505; DOI: 10.1136/jitc-2021-002505
High endothelial venule is a surrogate biomarker for T-cell inflamed tumor microenvironment and prognosis in gastric cancer
Hyung Soon Park, Yoo Min Kim, Sewha Kim, Won Suk Lee, So Jung Kong, Hannah Yang, Beodeul Kang, Jaekyung Cheon, Su-Jin Shin, Chan Kim, Hong Jae Chon

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003353; DOI: 10.1136/jitc-2021-003353
Characterization of intratumoral tertiary lymphoid structures in pancreatic ductal adenocarcinoma: cellular properties and prognostic significance
Xuan Zou, Xuan Lin, He Cheng, Yusheng Chen, Ruijie Wang, Mingjian Ma, Yu Liu, Zhengjie Dai, Yesboli Tasiheng, Yu Yan, Qinqin Hou, Fei Ding, Huan Chen, Xianjun Yu, Xu Wang, Chen Liu

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006698; DOI: 10.1136/jitc-2023-006698
G-MDSC-derived exosomes mediate the differentiation of M-MDSC into M2 macrophages promoting colitis-to-cancer transition
Yungang Wang, Hongli Liu, Zhe Zhang, Dezhi Bian, Keke Shao, Shengjun Wang, Yanxia Ding

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006166; DOI: 10.1136/jitc-2022-006166
Associations of subcutaneous fat area and Systemic Immune-inflammation Index with survival in patients with advanced gastric cancer receiving dual PD-1 and HER2 blockade
Meng He, Zi-Fan Chen, Li Zhang, Xiangyu Gao, Xiaoyi Chong, Hao-shen Li, Lin Shen, Jiafu Ji, Xiaotian Zhang, Bin Dong, Zi-Yu Li, Tang Lei

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e007054; DOI: 10.1136/jitc-2023-007054
G-CSF rescue of FOLFIRINOX-induced neutropenia leads to systemic immune suppression in mice and humans
Victoire Cardot-Ruffino, Naima Bollenrucher, Luisa Delius, S Jennifer Wang, Lauren K Brais, Joshua Remland, C Elizabeth Keheler, Keri M Sullivan, Thomas A Abrams, Leah H Biller, Peter C Enzinger, Nadine J McCleary, Anuj K Patel, Douglas A Rubinson, Benjamin Schlechter, Sarah Slater, Matthew B Yurgelun, James M Cleary, Kimberly Perez, Michael Dougan, Kimmie Ng, Brian M Wolpin, Harshabad Singh, Stephanie K Dougan

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006589; DOI: 10.1136/jitc-2022-006589
First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial
Lisa Paschold, Alexander Stein, Benjamin Thiele, Joseph Tintelnot, Svenja-Sibylla Henkes, Cornelia Coith, Christoph Schultheiß, Klaus Pantel, Sabine Riethdorf, Mascha Binder

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006678; DOI: 10.1136/jitc-2023-006678
Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of gastrointestinal cancer
Ronan J Kelly, Katherine Bever, Joseph Chao, Kristen K Ciombor, Cathy Eng, Marwan Fakih, Lipika Goyal, Joleen Hubbard, Renuka Iyer, Holly T Kemberling, Smitha Krishnamurthi, Geoffrey Ku, Mindy Mintz Mordecai, Van K Morris, Andrew Scott Paulson, Valerie Peterson, Manish A Shah, Dung T Le

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e006658; DOI: 10.1136/jitc-2022-006658

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