gastrointestinal neoplasms

CD11b⁺CTLA4⁺ myeloid cells are a key driver of tumor evasion in colorectal cancer
Hiroshi Imazeki, Yamato Ogiwara, Mami Kawamura, Narikazu Boku, Chie Kudo-Saito

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002841; DOI: 10.1136/jitc-2021-002841
PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer
Alexander Stein, Donjete Simnica, Christoph Schultheiß, Rebekka Scholz, Joseph Tintelnot, Eray Gökkurt, Lisa von Wenserski, Edith Willscher, Lisa Paschold, Markus Sauer, Sylvie Lorenzen, Jorge Riera-Knorrenschild, Reinhard Depenbusch, Thomas J Ettrich, Steffen Dörfel, Salah-Eddin Al-Batran, Meinolf Karthaus, Uwe Pelzer, Lisa Waberer, Axel Hinke, Marcus Bauer, Chiara Massa, Barbara Seliger, Claudia Wickenhauser, Carsten Bokemeyer, Susanna Hegewisch-Becker, Mascha Binder

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002844; DOI: 10.1136/jitc-2021-002844
Direct identification of neoantigen-specific TCRs from tumor specimens by high-throughput single-cell sequencing
Yong-Chen Lu, Zhili Zheng, Frank J Lowery, Jared J Gartner, Todd D Prickett, Paul F Robbins, Steven A Rosenberg

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002595; DOI: 10.1136/jitc-2021-002595
Tumor microenvironment evaluation promotes precise checkpoint immunotherapy of advanced gastric cancer
Dongqiang Zeng, Jiani Wu, Huiyan Luo, Yong Li, Jian Xiao, Jianjun Peng, Zilan Ye, Rui Zhou, Yunfang Yu, Gaofeng Wang, Na Huang, Jianhua Wu, Xiaoxiang Rong, Li Sun, Huiying Sun, Wenjun Qiu, Yichen Xue, Jianping Bin, Yulin Liao, Nailin Li, Min Shi, Kyoung-Mee Kim, Wangjun Liao

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002467; DOI: 10.1136/jitc-2021-002467
Nomogram to predict the outcomes of patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors
Filippo Pietrantonio, Sara Lonardi, Francesca Corti, Gabriele Infante, Maria Elena Elez, Marwan Fakih, Priya Jayachandran, Aakash Tushar Shah, Massimiliano Salati, Elisabetta Fenocchio, Lisa Salvatore, Giuseppe Curigliano, Chiara Cremolini, Margherita Ambrosini, Javier Ros, Rossana Intini, Floriana Nappo, Silvia Damian, Federica Morano, Giovanni Fucà, Michael Overman, Rosalba Miceli

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003370; DOI: 10.1136/jitc-2021-003370
Genomic and transcriptomic characterization of heterogeneous immune subgroups of microsatellite instability-high colorectal cancers
Jung Ho Kim, Mi-Kyoung Seo, Ji Ae Lee, Seung-Yeon Yoo, Hyeon Jeong Oh, Hyundeok Kang, Nam-Yun Cho, Jeong Mo Bae, Gyeong Hoon Kang, Sangwoo Kim

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003414; DOI: 10.1136/jitc-2021-003414
Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Carsten Krieg, Lukas M Weber, Bruno Fosso, Marinella Marzano, Gary Hardiman, Monica M Olcina, Enric Domingo, Sahar El Aidy, Khalil Mallah, Mark D Robinson, Silvia Guglietta

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e004717; DOI: 10.1136/jitc-2022-004717
Assessment of hyperprogression versus the natural course of disease development with nivolumab with or without ipilimumab versus placebo in phase III, randomized, controlled trials
Yoon-Koo Kang, Martin Reck, Paul Nghiem, Yan Feng, Gregory Plautz, Hye Ryun Kim, Taofeek K Owonikoko, Narikazu Boku, Li-Tzong Chen, Ming Lei, Han Chang, Wen Hong Lin, Amit Roy, Akintunde Bello, Jennifer Sheng

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004273; DOI: 10.1136/jitc-2021-004273
Tissue-resident memory T cells in gastrointestinal cancer immunology and immunotherapy: ready for prime time?
Syrine Abdeljaoued, Sara Arfa, Marie Kroemer, Myriam Ben Khelil, Angélique Vienot, Bruno Heyd, Romain Loyon, Alexandre Doussot, Christophe Borg

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e003472; DOI: 10.1136/jitc-2021-003472
Letter to the Editor from Colle et al
Raphael Colle, Thierry Andre, Yves Menu

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002997; DOI: 10.1136/jitc-2021-002997

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