gene expression profiling

Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target
Haizhou Wang, Yabo Zhou, Yangyang Zhang, Shilin Fang, Meng Zhang, Haiou Li, Fei Xu, Lan Liu, Jing Liu, Qiu Zhao, Fan Wang

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004302; DOI: 10.1136/jitc-2021-004302
Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma
Robert J Motzer, Toni K Choueiri, David F McDermott, Thomas Powles, Yann-Alexandre Vano, Saurabh Gupta, Jin Yao, Celine Han, Ron Ammar, Simon Papillon-Cavanagh, Shruti S Saggi, M Brent McHenry, Petra Ross-Macdonald, Megan Wind-Rotolo

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004316; DOI: 10.1136/jitc-2021-004316
Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma
Robert I Haddad, Tanguy Y Seiwert, Laura Q M Chow, Shilpa Gupta, Jared Weiss, Iris Gluck, Joseph P Eder, Barbara Burtness, Makoto Tahara, Bhumsuk Keam, Hyunseok Kang, Kei Muro, Andrew Albright, Robin Mogg, Mark Ayers, Lingkang Huang, Jared Lunceford, Razvan Cristescu, Jonathan Cheng, Ranee Mehra

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003026; DOI: 10.1136/jitc-2021-003026
Next steps for clinical translation of adenosine pathway inhibition in cancer immunotherapy
Ryan C. Augustin, Robert D. Leone, Aung Naing, Lawrence Fong, Riyue Bao, Jason J. Luke

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e004089; DOI: 10.1136/jitc-2021-004089
Immunologic constant of rejection signature is prognostic in soft-tissue sarcoma and refines the CINSARC signature
Francois Bertucci, Vincent Niziers, Alexandre de Nonneville, Pascal Finetti, Léna Mescam, Olivier Mir, Antoine Italiano, Axel Le Cesne, Jean-Yves Blay, Michele Ceccarelli, Davide Bedognetti, Daniel Birnbaum, Emilie Mamessier

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003687; DOI: 10.1136/jitc-2021-003687
Genomic and transcriptomic characterization of heterogeneous immune subgroups of microsatellite instability-high colorectal cancers
Jung Ho Kim, Mi-Kyoung Seo, Ji Ae Lee, Seung-Yeon Yoo, Hyeon Jeong Oh, Hyundeok Kang, Nam-Yun Cho, Jeong Mo Bae, Gyeong Hoon Kang, Sangwoo Kim

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003414; DOI: 10.1136/jitc-2021-003414
Combinatorial immunotherapy induces tumor-infiltrating CD8⁺ T cells with distinct functional, migratory, and stem-like properties
Natalija Van Braeckel-Budimir, Joseph Samuel Dolina, Jie Wei, Xiao Wang, Shih-Hsun Chen, Pamela Santiago, Guanghuan Tu, Luca Micci, Amir A Al-Khami, Sophia Pfister, Sripad Ram, Purnima Sundar, Graham Thomas, Hua Long, Wenjing Yang, Shobha Potluri, Shahram Salek-Ardakani

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003614; DOI: 10.1136/jitc-2021-003614
Primary vulvar squamous cell carcinomas with high T cell infiltration and active immune signaling are potential candidates for neoadjuvant PD-1/PD-L1 immunotherapy
Kim E Kortekaas, Saskia J Santegoets, Liselotte Tas, Ilina Ehsan, Pornpimol Charoentong, Helena C van Doorn, Mariette I E van Poelgeest, Dana A M Mustafa, Sjoerd H van der Burg

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003671; DOI: 10.1136/jitc-2021-003671
MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas
Qiang-Wei Wang, Li-Hua Sun, Ying Zhang, Zheng Wang, Zheng Zhao, Zhi-Liang Wang, Kuan-Yu Wang, Guan-Zhang Li, Jian-Bao Xu, Chang-Yuan Ren, Wen-Ping Ma, Hong-Jun Wang, Shou-Wei Li, Yong-Jian Zhu, Tao Jiang, Zhao-Shi Bao

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002451; DOI: 10.1136/jitc-2021-002451
Immunostimulatory effects of targeted thorium-227 conjugates as single agent and in combination with anti-PD-L1 therapy
Pascale Lejeune, Véronique Cruciani, Axel Berg-Larsen, Andreas Schlicker, Anne Mobergslien, Lisa Bartnitzky, Sandra Berndt, Sabine Zitzmann-Kolbe, Claudia Kamfenkel, Stefan Stargard, Stefanie Hammer, Jennifer S Jørgensen, Malene Jackerott, Carsten H Nielsen, Christoph A Schatz, Hartwig Hennekes, Jenny Karlsson, Alan S Cuthbertson, Dominik Mumberg, Urs B Hagemann

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002387; DOI: 10.1136/jitc-2021-002387

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