gene expression profiling

Wrinkle in the plan: miR-34a-5p impacts chemokine signaling by modulating CXCL10/CXCL11/CXCR3-axis in CD4⁺, CD8⁺ T cells, and M1 macrophages
Martin Hart, Laura Nickl, Barbara Walch-Rueckheim, Lena Krammes, Stefanie Rheinheimer, Caroline Diener, Tanja Taenzer, Tim Kehl, Martina Sester, Hans-Peter Lenhof, Andreas Keller, Eckart Meese

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (2) e001617; DOI: 10.1136/jitc-2020-001617
Prognostic significance and immune correlates of CD73 expression in renal cell carcinoma
Abhishek Tripathi, Edwin Lin, Wanling Xie, Abdallah Flaifel, John A Steinharter, Emily N Stern Gatof, Gabrielle Bouchard, Justin H Fleischer, Nieves Martinez-Chanza, Connor Gray, Charlene Mantia, Linda Thompson, Xiao X Wei, Marios Giannakis, Bradley A McGregor, Toni K Choueiri, Neeraj Agarwal, David F McDermott, Sabina Signoretti, Lauren C Harshman

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (2) e001467; DOI: 10.1136/jitc-2020-001467
Deep immunophenotyping at the single-cell level identifies a combination of anti-IL-17 and checkpoint blockade as an effective treatment in a preclinical model of data-guided personalized immunotherapy
Koji Nagaoka, Masataka Shirai, Kiyomi Taniguchi, Akihiro Hosoi, Changbo Sun, Yukari Kobayashi, Kazuhiro Maejima, Masashi Fujita, Hidewaki Nakagawa, Sachiyo Nomura, Kazuhiro Kakimi

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e001358; DOI: 10.1136/jitc-2020-001358
Clinical, FDG-PET and molecular markers of immune checkpoint inhibitor response in patients with metastatic Merkel cell carcinoma
Alison M Weppler, Andrew Pattison, Prachi Bhave, Paolo De Ieso, Jeanette Raleigh, Athena Hatzimihalis, Anthony J Gill, Shiva Balachander, Jason Callahan, Margaret Chua, George Au-Yeung, Grant A McArthur, Rodney J Hicks, Richard W Tothill, Shahneen Sandhu

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e000700; DOI: 10.1136/jitc-2020-000700
Host genetics and tumor environment determine the functional impact of neutrophils in mouse tumor models
Marit van Elsas, Jan Willem Kleinovink, Matthijs Moerland, Gary Feiss, Guillaume Beyrend, Ramon Arens, Hailiang Mei, Peter H Nibbering, Silvana M Jirka, Thorbald van Hall, Sjoerd H van der Burg

Journal for ImmunoTherapy of Cancer Sep 2020, 8 (2) e000877; DOI: 10.1136/jitc-2020-000877
Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma
Anuraag Parikh, JuneHo Shin, William Faquin, Derrick T Lin, Itay Tirosh, John B Sunwoo, Sidharth V Puram

Journal for ImmunoTherapy of Cancer Sep 2020, 8 (2) e001048; DOI: 10.1136/jitc-2020-001048
Differential gene expression of tumor-infiltrating CD8⁺ T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosis
Reem Saleh, Varun Sasidharan Nair, Salman M Toor, Rowaida Z Taha, Khaled Murshed, Mahmood Al-Dhaheri, Mahwish Khawar, Mahir Abdulla Petkar, Mohamed Abu Nada, Fares Al-Ejeh, Eyad Elkord

Journal for ImmunoTherapy of Cancer Sep 2020, 8 (2) e001294; DOI: 10.1136/jitc-2020-001294
ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19
Riyue Bao, Kyle Hernandez, Lei Huang, Jason John Luke

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e001020; DOI: 10.1136/jitc-2020-001020
Lung metastases share common immune features regardless of primary tumor origin
Sandra García-Mulero, M Henar Alonso, Julián Pardo, Cristina Santos, Xavier Sanjuan, Ramón Salazar, Victor Moreno, Josep María Piulats, Rebeca Sanz-Pamplona

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000491; DOI: 10.1136/jitc-2019-000491
High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot
Simon P Keam, Heloise Halse, Thu Nguyen, Minyu Wang, Nicolas Van Kooten Losio, Catherine Mitchell, Franco Caramia, David J Byrne, Sue Haupt, Georgina Ryland, Phillip K Darcy, Shahneen Sandhu, Piers Blombery, Ygal Haupt, Scott G Williams, Paul J Neeson

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000792; DOI: 10.1136/jitc-2020-000792

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gene expression profiling

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