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Human antibody-based therapy

  • A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer
    Pénélope Desroys du Roure, Laurie Lajoie, Aude Mallavialle, Lindsay B Alcaraz, Hanane Mansouri, Lise Fenou, Véronique Garambois, Lucie Rubio, Timothée David, Loïs Coenon, Florence Boissière-Michot, Marie-Christine Chateau, Giang Ngo, Marta Jarlier, Martin Villalba, Pierre Martineau, Valérie Laurent-Matha, Pascal Roger, Séverine Guiu, Thierry Chardès, Laurent Gros, Emmanuelle Liaudet-Coopman
    Journal for ImmunoTherapy of Cancer Jan 2024, 12 (1) e007135; DOI: 10.1136/jitc-2023-007135
  • Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies
    Yahya Ashraf, Hanane Mansouri, Valérie Laurent-Matha, Lindsay B. Alcaraz, Pascal Roger, Séverine Guiu, Danielle Derocq, Gautier Robin, Henri-Alexandre Michaud, Helène Delpech, Marta Jarlier, Martine Pugnière, Bruno Robert, Anthony Puel, Lucie Martin, Flavie Landomiel, Thomas Bourquard, Oussama Achour, Ingrid Fruitier-Arnaudin, Alexandre Pichard, Emmanuel Deshayes, Andrei Turtoi, Anne Poupon, Joëlle Simony-Lafontaine, Florence Boissière-Michot, Nelly Pirot, Florence Bernex, William Jacot, Stanislas du Manoir, Charles Theillet, Jean-Pierre Pouget, Isabelle Navarro-Teulon, Nathalie Bonnefoy, André Pèlegrin, Thierry Chardès, Pierre Martineau, Emmanuelle Liaudet-Coopman
    Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 29; DOI: 10.1186/s40425-019-0498-z