Immune Checkpoint Inhibition

Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis
Clint T. Allen, Sunmin Lee, Scott M. Norberg, Damian Kovalovsky, Hong Ye, Paul E. Clavijo, Siwen Hu-Lieskovan, Richard Schlegel, Jeffrey Schlom, Julius Strauss, James L. Gulley, Jane Trepel, Christian S. Hinrichs

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 119; DOI: 10.1186/s40425-019-0603-3
Donor-derived cell-free DNA detects kidney transplant rejection during nivolumab treatment
Daan P. Hurkmans, Jeroen G. H. P. Verhoeven, Kitty de Leur, Karin Boer, Arjen Joosse, Carla C. Baan, Jan H. von der Thüsen, Ron H. N. van Schaik, Ron H. J. Mathijssen, Astrid A. M. van der Veldt, Dennis A. Hesselink

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 182; DOI: 10.1186/s40425-019-0653-6
Immunogenicity of prostate cancer is augmented by BET bromodomain inhibition
Wendy Mao, Ali Ghasemzadeh, Zachary T. Freeman, Aleksandar Obradovic, Matthew G. Chaimowitz, Thomas R. Nirschl, Emily McKiernan, Srinivasan Yegnasubramanian, Charles G. Drake

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 277; DOI: 10.1186/s40425-019-0758-y
Phase 1/2 study of epacadostat in combination with ipilimumab in patients with unresectable or metastatic melanoma
Geoffrey T. Gibney, Omid Hamid, Jose Lutzky, Anthony J. Olszanski, Tara C. Mitchell, Thomas F. Gajewski, Bartosz Chmielowski, Brent A. Hanks, Yufan Zhao, Robert C. Newton, Janet Maleski, Lance Leopold, Jeffrey S. Weber

Journal for ImmunoTherapy of Cancer Dec 2019, 7 (1) 80; DOI: 10.1186/s40425-019-0562-8
Biomarkers of immunotherapy in urothelial and renal cell carcinoma: PD-L1, tumor mutational burden, and beyond
Jason Zhu, Andrew J. Armstrong, Terence W. Friedlander, Won Kim, Sumanta K. Pal, Daniel J. George, Tian Zhang

Journal for ImmunoTherapy of Cancer Dec 2018, 6 (1) 4; DOI: 10.1186/s40425-018-0314-1
Response after treatment with pembrolizumab in a patient with myelophthisis due to melanoma: the role of checkpoint inhibition in the bone
Samuel Rosner, Filiz Sen, Michael Postow

Journal for ImmunoTherapy of Cancer Dec 2017, 5 (1) 34; DOI: 10.1186/s40425-017-0236-3
Deletion of NF-kB p50 alters murine glioblastoma tumor-associated macrophage polarization, reduces tumor growth and prolongs survival
Theresa Barberi, Allison Martin, Sarah Harris-Bookman, Michael Lim, Alan D Friedman

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P395; DOI: 10.1186/2051-1426-3-S2-P395
Antibody blockade of semaphorin 4D breaks down barriers to enhance tumoricidal immune infiltration and supports rational immunotherapy combinations
Elizabeth E Evans, Siwen Hu-Lieskovan, Holm Bussler, Sebold Torno, Crystal Mallow, Christine Reilly, Maria Scrivens, Ekaterina Klimatcheva, Laurie A Winter, Renee Kirk, Alan Howell, Leslie Balch, Janaki Veeraraghavan, Alan S Jonason, John E Leonard, Mark Paris, Terrence L Fisher, Antoni Ribas, Ernest S Smith, Maurice Zauderer

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P220; DOI: 10.1186/2051-1426-3-S2-P220
Antibody-mediated phosphatidylserine blockade significantly enhances the efficacy of downstream immune checkpoint inhibition in K1735 mouse melanoma
Xianming Huang, Jian Gong, Dan Ye, Van Nguyen, Shen Yin, Rich Archer, Chris Hughes, Rolf Brekken, Jeff Hutchins, Alan Schroit, Bruce Freimark

Journal for ImmunoTherapy of Cancer Dec 2014, 2 (Suppl 3) P205; DOI: 10.1186/2051-1426-2-S3-P205
Circulating and tumor-based biomarkers predict clinical activity in cancer patients treated with the engineered anti-PD-L1 antibody MPDL3280A
Marcin Kowanetz, Christina Rabe, Yuanyuan Xiao, Qun J Wu, Hartmut Koeppen, Cecilia Leddy, Rajesh D Patel, John Powderly, Holbrook Kohrt, Scott Gettinger, Jean-Charles Soria, Roy S Herbst, Rupal Desai, Mitchell Denker, Jane Ruppel, Marigold Boe, Rin Nakamura, Ling Fu, Teiko Sumiyoshi, Ahmad Mokatrin, Xiaodong Shen, Gregg Fine, Daniel S Chen, Priti S Hegde

Journal for ImmunoTherapy of Cancer Dec 2014, 2 (Suppl 3) P136; DOI: 10.1186/2051-1426-2-S3-P136

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