immune evation

EBV promotes TCR-T-cell therapy resistance by inducing CD163+M2 macrophage polarization and MMP9 secretion
Yuanyuan Chen, Dijun Ouyang, Yan Wang, Qiuzhong Pan, Jingjing Zhao, Hao Chen, Xinyi Yang, Yan Tang, Qijing Wang, Yongqiang Li, Jia He, Jin-Qi You, Yingzi Li, Chi Xu, Yan Ren, Sisi Xie, Song Li, Jiamin Lian, Desheng Weng, Tong Xiang, Jian-Chuan Xia

Journal for ImmunoTherapy of Cancer Jun 2024, 12 (6) e008375; DOI: 10.1136/jitc-2023-008375
BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1
Young-Seung Kim, Seung-Hoon Lee, Andrew H Park, Chunai Wu, Bong-Ki Hong, Hyunjin Jung, Steven H Lin, Stephen S Yoo

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008303; DOI: 10.1136/jitc-2023-008303
L-5-hydroxytryptophan promotes antitumor immunity by inhibiting PD-L1 inducible expression
Jing Huang, Xiaobo Wang, Bing Li, Shiyu Shen, Ruina Wang, Hongru Tao, Junchi Hu, Jin Yu, Hualiang Jiang, Kaixian Chen, Cheng Luo, Yongjun Dang, Yuanyuan Zhang

Journal for ImmunoTherapy of Cancer Jun 2022, 10 (6) e003957; DOI: 10.1136/jitc-2021-003957
Cancer cells resist antibody-mediated destruction by neutrophils through activation of the exocyst complex
Dieke J van Rees, Panagiota Bouti, Bart Klein, Paul J H Verkuijlen, Michel van Houdt, Karin Schornagel, Anton T J Tool, David Venet, Christos Sotiriou, Sarra El-Abed, Miguel Izquierdo, Sébastien Guillaume, Cristina Saura, Serena Di Cosimo, Jens Huober, Rebecca Roylance, Sung-Bae Kim, Taco W Kuijpers, Robin van Bruggen, Timo K van den Berg, Hanke L Matlung

Journal for ImmunoTherapy of Cancer Jun 2022, 10 (6) e004820; DOI: 10.1136/jitc-2022-004820
T lymphocytes induce human cancer cells derived from solid malignant tumors to secrete galectin-9 which facilitates immunosuppression in cooperation with other immune checkpoint proteins
Stephanie Schlichtner, Inna M Yasinska, Gurprit S Lall, Steffen M Berger, Sabrina Ruggiero, Dietmar Cholewa, Nijas Aliu, Bernhard F Gibbs, Elizaveta Fasler-Kan, Vadim V Sumbayev

Journal for ImmunoTherapy of Cancer Jan 2023, 11 (1) e005714; DOI: 10.1136/jitc-2022-005714
Treg-selective IL-2 starvation synergizes with CD40 activation to sustain durable responses in lymphoma models
Kristin Stirm, Peter Leary, Daria Wüst, Dominique Stark, Nicole Joller, Ufuk Karakus, Onur Boyman, Alexandar Tzankov, Anne Müller

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e006263; DOI: 10.1136/jitc-2022-006263
Mast cell-T cell axis alters development of colitis-dependent and colitis-independent colorectal tumours: potential for therapeutically targeting via mast cell inhibition
Juliana Y Sakita, Jefferson Elias-Oliveira, Daniela Carlos, Emerson de Souza Santos, Luciana Yamamoto Almeida, Tathiane M Malta, Mariângela O Brunaldi, Sergio Albuquerque, Cleide Lúcia Araújo Silva, Marcus V Andrade, Vania L D Bonato, Sergio Britto Garcia, Fernando Queiroz Cunha, Guilherme Cesar Martelossi Cebinelli, Ronaldo B Martins, Jason Matthews, Leandro Colli, Francis L Martin, Sergio A Uyemura, Vinicius Kannen

Journal for ImmunoTherapy of Cancer Oct 2022, 10 (10) e004653; DOI: 10.1136/jitc-2022-004653
Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis
Madeline Dahut, Kristen Fousek, Lucas A Horn, Shantel Angstadt, Haiyan Qin, Duane H Hamilton, Jeffrey Schlom, Claudia Palena

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007386; DOI: 10.1136/jitc-2023-007386
Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts
Rachel A Woolaver, Xiaoguang Wang, Alexandra L Krinsky, Brittany C Waschke, Samantha M Y Chen, Vince Popolizio, Andrew G Nicklawsky, Dexiang Gao, Zhangguo Chen, Antonio Jimeno, Xiao-Jing Wang, Jing Hong Wang

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001615; DOI: 10.1136/jitc-2020-001615
Identification of neuroblastoma cell lines with uncommon TAZ⁺/mesenchymal stromal cell phenotype with strong suppressive activity on natural killer cells
Claudia Canzonetta, Andrea Pelosi, Sabina Di Matteo, Irene Veneziani, Nicola Tumino, Paola Vacca, Enrico Munari, Marco Pezzullo, Charles Theuer, Rita De Vito, Vito Pistoia, Luigi Tomao, Franco Locatelli, Lorenzo Moretta, Ignazio Caruana, Bruno Azzarone

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001313; DOI: 10.1136/jitc-2020-001313

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