Immune Tolerance

Combining inhibition of galectin-3 with and before a therapeutic vaccination is critical for the prostate-tumor-free outcome
Carolina Tiraboschi, Lucas Gentilini, Carla Velazquez, Enrique Corapi, Felipe Martín Jaworski, José Daniel Garcia Garcia, Yorfer Rondón, Anne Chauchereau, Diego José Laderach, Daniel Compagno

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001535; DOI: 10.1136/jitc-2020-001535
Synergizing sunitinib and radiofrequency ablation to treat hepatocellular cancer by triggering the antitumor immune response
Xiaoqiang Qi, Ming Yang, Lixin Ma, Madeline Sauer, Diego Avella, Jussuf T Kaifi, Jeffrey Bryan, Kun Cheng, Kevin F Staveley-O’Carroll, Eric T Kimchi, Guangfu Li

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e001038; DOI: 10.1136/jitc-2020-001038
LAG-3: from molecular functions to clinical applications
Takumi Maruhashi, Daisuke Sugiura, Il-mi Okazaki, Taku Okazaki

Journal for ImmunoTherapy of Cancer Sep 2020, 8 (2) e001014; DOI: 10.1136/jitc-2020-001014
Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity
Henrique Lemos, Rong Ou, Caroline McCardle, Yijun Lin, Jessica Calver, Jack Minett, Ahmed Chadli, Lei Huang, Andrew L Mellor

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e001182; DOI: 10.1136/jitc-2020-001182
Molecular mechanisms of human herpes viruses inferring with host immune surveillance
Simon Jasinski-Bergner, Ofer Mandelboim, Barbara Seliger

Journal for ImmunoTherapy of Cancer Jul 2020, 8 (2) e000841; DOI: 10.1136/jitc-2020-000841
Agonist anti-GITR antibody significantly enhances the therapeutic efficacy of Listeria monocytogenes-based immunotherapy
Rajeev Shrimali, Shamim Ahmad, Zuzana Berrong, Grigori Okoev, Adelaida Matevosyan, Ghazaleh Shoja E. Razavi, Robert Petit, Seema Gupta, Mikayel Mkrtichyan, Samir N. Khleif

Journal for ImmunoTherapy of Cancer Dec 2017, 5 (1) 64; DOI: 10.1186/s40425-017-0266-x
Placental protein-1 (plac1) modulates immune tolerance in mammary tumor cells
Hongyan Yuan, Robert Glazer, Xiaoyi Wang, Lu Jin, James Li, Nairuthya Vijayendra, Venkata Doodala, Spencer Weiss

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P221; DOI: 10.1186/2051-1426-3-S2-P221
Direct activation of STING in the tumor microenvironment partially overcomes immune tolerance in neu-N transgenic mice
Jeremy Foote, James M Leatherman, Todd D Amstrong, Laureen Ojalvo, David Kanne, Elizabeth M Jaffee, Tom Dubensky, Leisha Emens

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P356; DOI: 10.1186/2051-1426-3-S2-P356
Lymphoid-like fibroblast reticular cells in the secondary lymphoid tissues and tumor microenvironment induce immunosuppression via maintaining the tolerogenic function of myeloid populations
Yan Cui, Gang Guo

Journal for ImmunoTherapy of Cancer Dec 2014, 2 (Suppl 3) P201; DOI: 10.1186/2051-1426-2-S3-P201
Epitope-optimization creates highly immunogenic alpha fetoprotein antigen to break immune tolerance and potently activates CD8 T cells to prevents autochthonous hepatocellular carcinoma
Yuan Hong, Yibing Peng, Sheng Z Guo, Junfeng Pang, Jose Guevara-patino, David H Munn, Nahid Mivechi, David Bartlett, Yukai He

Journal for ImmunoTherapy of Cancer Nov 2013, 1 (Suppl 1) P216; DOI: 10.1186/2051-1426-1-S1-P216

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