immunologic techniques

Lower frequencies of circulating suppressive regulatory T cells and higher frequencies of CD4⁺ naïve T cells at baseline are associated with severe immune-related adverse events in immune checkpoint inhibitor-treated melanoma
Magdalena Kovacsovics-Bankowski, Johanna M Sweere, Connor P Healy, Natalia Sigal, Li-Chun Cheng, William D Chronister, Shane A Evans, John Marsiglio, Berit Gibson, Umang Swami, Alyssa Erickson-Wayman, Jordan P McPherson, Yoko S Derose, Annaleah Larson Eliason, Carlos O Medina, Ramji Srinivasan, Matthew H Spitzer, Ngan Nguyen, John Hyngstrom, Siwen Hu-Lieskovan

Journal for ImmunoTherapy of Cancer Jan 2024, 12 (1) e008056; DOI: 10.1136/jitc-2023-008056
MRI techniques for immunotherapy monitoring
Doreen Lau, Pippa G Corrie, Ferdia A Gallagher

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e004708; DOI: 10.1136/jitc-2022-004708
Method for estimation of apoptotic cell fraction of cytotherapy using in vivo fluorine-19 magnetic resonance: pilot study in a patient with head and neck carcinoma receiving tumor-infiltrating lymphocytes labeled with perfluorocarbon nanoemulsion
Eric T Ahrens, Brooke M Helfer, Charles F O’Hanlon, Deanne R Lister, Julie L Bykowski, Karen Messer, Benjamin I Leach, Jiawen Chen, Hongyan Xu, Gregory A Daniels, Ezra E W Cohen

Journal for ImmunoTherapy of Cancer Jun 2023, 11 (6) e007015; DOI: 10.1136/jitc-2023-007015
Differences in TCR repertoire and T cell activation underlie the divergent outcomes of antitumor immune responses in tumor-eradicating versus tumor-progressing hosts
Rachel A Woolaver, Xiaoguang Wang, Alexandra L Krinsky, Brittany C Waschke, Samantha M Y Chen, Vince Popolizio, Andrew G Nicklawsky, Dexiang Gao, Zhangguo Chen, Antonio Jimeno, Xiao-Jing Wang, Jing Hong Wang

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001615; DOI: 10.1136/jitc-2020-001615
Gut microbiome-depleting antibiotic regimens are not tolerated by all mouse strains: learn from (our) bitter experience
Andrew A Almonte, George Cavic, Teresa Neeman, Anselm Enders, Aude M Fahrer

Journal for ImmunoTherapy of Cancer Nov 2022, 10 (11) e005575; DOI: 10.1136/jitc-2022-005575
Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids
Qingda Meng, Shanshan Xie, G Kenneth Gray, Mohammad H Dezfulian, Omar Gandarilla, Weilin Li, Ling Huang, Dipikaa Akshinthala, Elizabeth Ferrer, Catherine Conahan, Sofia Perea Del Pino, Joseph Grossman, Stephen J Elledge, Manuel Hidalgo, Senthil K Muthuswamy

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003213; DOI: 10.1136/jitc-2021-003213
Evaluating T-cell cross-reactivity between tumors and immune-related adverse events with TCR sequencing: pitfalls in interpretations of functional relevance
Tricia Cottrell, Jiajia Zhang, Boyang Zhang, Genevieve J Kaunitz, Poromendro Burman, Hok-Yee Chan, Franco Verde, Jody E Hooper, Hans Hammers, Mohamad E Allaf, Hongkai Ji, Janis Taube, Kellie N Smith

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002642; DOI: 10.1136/jitc-2021-002642
Novel non-terminal tumor sampling procedure using fine needle aspiration supports immuno-oncology biomarker discovery in preclinical mouse models
Suzanne Isabelle Sitnikova, Sophie Munnings-Tomes, Elena Galvani, Stacy Kentner, Kathy Mulgrew, Chris Rands, Judit España Agustí, Tianhui Zhang, Kristina M Ilieva, Guglielmo Rosignoli, Hormas Ghadially, Matthew J Robinson, Tim Slidel, Robert W Wilkinson, Simon J Dovedi

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002894; DOI: 10.1136/jitc-2021-002894
Designed improvement to T-cell immunotherapy by multidimensional single cell profiling
Irfan N Bandey, Jay R T Adolacion, Gabrielle Romain, Melisa Martinez Paniagua, Xingyue An, Arash Saeedi, Ivan Liadi, Zheng You, Rasindu B Rajanayake, Patrick Hwu, Harjeet Singh, Laurence JN Cooper, Navin Varadarajan

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001877; DOI: 10.1136/jitc-2020-001877
Depth of tumor implantation affects response to in situ vaccination in a syngeneic murine melanoma model
Peter M Carlson, Manasi Mohan, Matthew Rodriguez, Vladimir Subbotin, Claire X Sun, Ravi B Patel, Jen Birstler, Jacquelyn A Hank, Alexander L Rakhmilevich, Zachary S Morris, Amy K Erbe, Paul M Sondel

Journal for ImmunoTherapy of Cancer Apr 2021, 9 (4) e002107; DOI: 10.1136/jitc-2020-002107

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immunologic techniques