Immunology

Conditional immune toxicity rate in patients with metastatic renal and urothelial cancer treated with immune checkpoint inhibitors
Pier Vitale Nuzzo, Gregory R Pond, Sarah Abou Alaiwi, Amin H Nassar, Ronan Flippot, Catherine Curran, Kerry L Kilbridge, Xiao X Wei, Bradley A McGregor, Toni Choueiri, Lauren C Harshman, Guru Sonpavde

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000371; DOI: 10.1136/jitc-2019-000371
T cell receptor repertoire characteristics both before and following immunotherapy correlate with clinical response in mesothelioma
Heleen Vroman, Giulia Balzaretti, Robert A Belderbos, Paul L Klarenbeek, Menno van Nimwegen, Koen Bezemer, Robin Cornelissen, Ilse T G Niewold, Barbera D van Schaik, Antione H van Kampen, Joachim G J V Aerts, Niek de Vries, Rudi W Hendriks

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000251; DOI: 10.1136/jitc-2019-000251
Immunosuppressant indulges EBV reactivation and related lymphoproliferative disease by inhibiting Vδ2⁺ T cells activities after hematopoietic transplantation for blood malignancies
Jiangying Liu, Haitao Gao, Lan-Ping Xu, Xiao-Dong Mo, Ruoyang Liu, Shuang Liang, Ning Wu, Ming Wang, Zhidong Wang, Ying-Jun Chang, Yu Wang, Xiao-Hui Zhang, Xiao-Jun Huang

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000208; DOI: 10.1136/jitc-2019-000208
Characterization of tumor mutation burden, PD-L1 and DNA repair genes to assess relationship to immune checkpoint inhibitors response in metastatic renal cell carcinoma
Matthew Kyle Labriola, Jason Zhu, Rajan Gupta, Shannon McCall, Jennifer Jackson, Eric F Kong, James R White, Gustavo Cerqueira, Kelly Gerding, John K Simmons, Daniel George, Tian Zhang

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000319; DOI: 10.1136/jitc-2019-000319
Combined immunotherapy with nivolumab and ipilimumab with and without local therapy in patients with melanoma brain metastasis: a DeCOG* study in 380 patients
Teresa Amaral, Felix Kiecker, Sarah Schaefer, Henner Stege, Katharina Kaehler, Patrick Terheyden, Anja Gesierich, Ralf Gutzmer, Sebastian Haferkamp, Jochen Uttikal, Carola Berking, David Rafei-Shamsabadi, Lydia Reinhardt, Friedegund Meier, Ante Karoglan, Christian Posch, Thilo Gambichler, Claudia Pfoehler, Kai Thoms, Julia Tietze, Dirk Debus, Rudolf Herbst, Steffen Emmert, Carmen Loquai, Jessica C Hassel, Frank Meiss, Thomas Tueting, Vanessa Heinrich, Thomas Eigentler, Claus Garbe, Lisa Zimmer

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000333; DOI: 10.1136/jitc-2019-000333
EpCAM-high liver cancer stem cells resist natural killer cell–mediated cytotoxicity by upregulating CEACAM1
Dong Jun Park, Pil Soo Sung, Jung-Hee Kim, Gil Won Lee, Jeong Won Jang, Eun Sun Jung, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000301; DOI: 10.1136/jitc-2019-000301
Longitudinal NK cell kinetics and cytotoxicity in children with neuroblastoma enrolled in a clinical phase II trial
Rosa Nguyen, Natasha Sahr, April Sykes, Mary Beth McCarville, Sara M Federico, Amanda Sooter, David Cullins, Barbara Rooney, William E Janssen, Aimee C Talleur, Brandon M Triplett, Gwendolyn Anthony, Michael A Dyer, Alberto S Pappo, Wing H Leung, Wayne L Furman

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000176; DOI: 10.1136/jitc-2019-000176
Cellular cytotoxicity is a form of immunogenic cell death
Luna Minute, Alvaro Teijeira, Alfonso R Sanchez-Paulete, Maria C Ochoa, Maite Alvarez, Itziar Otano, Iñaki Etxeberrria, Elixabet Bolaños, Arantza Azpilikueta, Saray Garasa, Noelia Casares, Jose Luis Perez Gracia, Maria E Rodriguez-Ruiz, Pedro Berraondo, Ignacio Melero

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000325; DOI: 10.1136/jitc-2019-000325
Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia
Veronika Mancikova, Helena Peschelova, Veronika Kozlova, Aneta Ledererova, Adriana Ladungova, Jan Verner, Tomas Loja, Frantisek Folber, Jiri Mayer, Sarka Pospisilova, Michal Smida

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000471; DOI: 10.1136/jitc-2019-000471
Characterization of human cancer xenografts in humanized mice
Jonathan Rios-Doria, Christina Stevens, Christopher Maddage, Kerri Lasky, Holly K Koblish

Journal for ImmunoTherapy of Cancer Mar 2020, 8 (1) e000416; DOI: 10.1136/jitc-2019-000416

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