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CCR1 and CCR5 mediate cancer-induced myelopoiesis and differentiation of myeloid cells in the tumor
Serena Zilio, Silvio Bicciato, Donald Weed, Paolo Serafini

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003131; DOI: 10.1136/jitc-2021-003131
Role of Fcγ receptors in HER2-targeted breast cancer therapy
Antonino Musolino, William J Gradishar, Hope S Rugo, Jeffrey L Nordstrom, Edwin P Rock, Fernanda Arnaldez, Mark D Pegram

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003171; DOI: 10.1136/jitc-2021-003171
Off-the-shelf Vδ1 gamma delta T cells engineered with glypican-3 (GPC-3)-specific chimeric antigen receptor (CAR) and soluble IL-15 display robust antitumor efficacy against hepatocellular carcinoma
Amani Makkouk, Xue (Cher) Yang, Taylor Barca, Anthony Lucas, Mustafa Turkoz, Jonathan T S Wong, Kevin P Nishimoto, Mary M Brodey, Maryam Tabrizizad, Smitha R Y Gundurao, Lu Bai, Arun Bhat, Zili An, Stewart Abbot, Daulet Satpayev, Blake T Aftab, Marissa Herrman

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003441; DOI: 10.1136/jitc-2021-003441
Uncoupled biological and chronological aging of neutrophils in cancer promotes tumor progression
Laura A Mittmann, Florian Haring, Johanna B Schaubächer, Roman Hennel, Bojan Smiljanov, Gabriele Zuchtriegel, Martin Canis, Olivier Gires, Fritz Krombach, Lesca Holdt, Sven Brandau, Thomas Vogl, Kirsten Lauber, Bernd Uhl, Christoph A Reichel

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003495; DOI: 10.1136/jitc-2021-003495
Activated but impaired IFN-γ production of mucosal-associated invariant T cells in patients with hepatocellular carcinoma
Wenyong Huang, Dongmei Ye, Wenjing He, Xiaoshun He, Xiaomin Shi, Yifang Gao

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003685; DOI: 10.1136/jitc-2021-003685
Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity
Shih-Hsun Chen, Pawel K Dominik, Jessica Stanfield, Sheng Ding, Wenjing Yang, Nadia Kurd, Ryan Llewellyn, Jonathan Heyen, Carole Wang, Zea Melton, Thomas Van Blarcom, Kevin C Lindquist, Javier Chaparro-Riggers, Shahram Salek-Ardakani

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003464; DOI: 10.1136/jitc-2021-003464
Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity
Clément Anfray, Francesco Mainini, Elisabeth Digifico, Akihiro Maeda, Marina Sironi, Marco Erreni, Achille Anselmo, Aldo Ummarino, Sara Gandoy, Francisco Expósito, Miriam Redrado, Diego Serrano, Alfonso Calvo, Marvin Martens, Susana Bravo, Alberto Mantovani, Paola Allavena, Fernando Torres Andón

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002408; DOI: 10.1136/jitc-2021-002408
CARs and beyond: tailoring macrophage-based cell therapeutics to combat solid malignancies
Shifaa M. Abdin, Daniela Paasch, Michael Morgan, Nico Lachmann

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002741; DOI: 10.1136/jitc-2021-002741
NK cells enhance CAR-T cell antitumor efficacy by enhancing immune/tumor cells cluster formation and improving CAR-T cell fitness
Mireia Bachiller, Lorena Perez-Amill, Anthony Matthew Battram, Sebastian Ciro Carné, Amer Najjar, Els Verhoeyen, Manel Juan, Alvaro Urbano-Ispizua, Beatriz Martin-Antonio

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002866; DOI: 10.1136/jitc-2021-002866
High potency STING agonists engage unique myeloid pathways to reverse pancreatic cancer immune privilege
Casey R Ager, Akash Boda, Kimal Rajapakshe, Spencer Thomas Lea, Maria Emilia Di Francesco, Priyamvada Jayaprakash, Ravaen B Slay, Brittany Morrow, Rishika Prasad, Meghan A Dean, Colm R Duffy, Cristian Coarfa, Philip Jones, Michael A Curran

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003246; DOI: 10.1136/jitc-2021-003246

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