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Rethinking immune checkpoint blockade: ‘Beyond the T cell’
Xiuting Liu, Graham D Hogg, David G DeNardo

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001460; DOI: 10.1136/jitc-2020-001460
In situ immunogenic clearance induced by a combination of photodynamic therapy and rho-kinase inhibition sensitizes immune checkpoint blockade response to elicit systemic antitumor immunity against intraocular melanoma and its metastasis
Seohyun Kim, Seong A Kim, Gi-Hoon Nam, Yeonsun Hong, Gi Beom Kim, Yoonjeong Choi, Seokyoung Lee, Yuri Cho, Minsu Kwon, Cherlhyun Jeong, Sehoon Kim, In-San Kim

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001481; DOI: 10.1136/jitc-2020-001481
Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity
Clément Anfray, Francesco Mainini, Elisabeth Digifico, Akihiro Maeda, Marina Sironi, Marco Erreni, Achille Anselmo, Aldo Ummarino, Sara Gandoy, Francisco Expósito, Miriam Redrado, Diego Serrano, Alfonso Calvo, Marvin Martens, Susana Bravo, Alberto Mantovani, Paola Allavena, Fernando Torres Andón

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e002408; DOI: 10.1136/jitc-2021-002408
1α,25(OH)₂D₃ reverses exhaustion and enhances antitumor immunity of human cytotoxic T cells
Peng Li, Xinhai Zhu, Guangchao Cao, Ruan Wu, Ke Li, Wenhui Yuan, Biyun Chen, Guodong Sun, Xichun Xia, Hua Zhang, Xiao Wang, Zhinan Yin, Ligong Lu, Yunfei Gao

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003477; DOI: 10.1136/jitc-2021-003477
CCR1 and CCR5 mediate cancer-induced myelopoiesis and differentiation of myeloid cells in the tumor
Serena Zilio, Silvio Bicciato, Donald Weed, Paolo Serafini

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003131; DOI: 10.1136/jitc-2021-003131
Intermediate monocytes induced by IFN-γ inhibit cancer metastasis by promoting NK cell activation through FOXO1 and interleukin-27
Rikang Wang, Weili Bao, Mouli Pal, Yunfeng Liu, Karina Yazdanbakhsh, Hui Zhong

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003539; DOI: 10.1136/jitc-2021-003539
Role of Fcγ receptors in HER2-targeted breast cancer therapy
Antonino Musolino, William J Gradishar, Hope S Rugo, Jeffrey L Nordstrom, Edwin P Rock, Fernanda Arnaldez, Mark D Pegram

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003171; DOI: 10.1136/jitc-2021-003171
Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity
Shih-Hsun Chen, Pawel K Dominik, Jessica Stanfield, Sheng Ding, Wenjing Yang, Nadia Kurd, Ryan Llewellyn, Jonathan Heyen, Carole Wang, Zea Melton, Thomas Van Blarcom, Kevin C Lindquist, Javier Chaparro-Riggers, Shahram Salek-Ardakani

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003464; DOI: 10.1136/jitc-2021-003464
Activated but impaired IFN-γ production of mucosal-associated invariant T cells in patients with hepatocellular carcinoma
Wenyong Huang, Dongmei Ye, Wenjing He, Xiaoshun He, Xiaomin Shi, Yifang Gao

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003685; DOI: 10.1136/jitc-2021-003685
TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer
Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Michael Conroy, Caitriona Goggin, Colm MacEochagain, John Kennedy, Sophie Lucas, David K Finlay, Clair M Gardiner

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e002044; DOI: 10.1136/jitc-2020-002044

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