investigational

Phase I study of ABBV-428, a mesothelin-CD40 bispecific, in patients with advanced solid tumors
Jason J Luke, Fabrice Barlesi, Ki Chung, Anthony W Tolcher, Karen Kelly, Antoine Hollebecque, Christophe Le Tourneau, Vivek Subbiah, Frank Tsai, Steven Kao, Philippe A Cassier, Mustafa Khasraw, Hedy L Kindler, Hua Fang, Frances Fan, Kathryn Allaire, Maulik Patel, Shiming Ye, Debra T Chao, William R Henner, Joel S Hayflick, Michael A McDevitt, Lawrence Fong

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e002015; DOI: 10.1136/jitc-2020-002015
CX-072 (pacmilimab), a Probody PD-L1 inhibitor, in combination with ipilimumab in patients with advanced solid tumors (PROCLAIM-CX-072): a first-in-human, dose-finding study
Rachel E Sanborn, Omid Hamid, Elisabeth GE de Vries, Patrick A Ott, Javier Garcia-Corbacho, Valentina Boni, Johanna Bendell, Karen A Autio, Daniel C Cho, Ruth Plummer, Mark Stroh, Lawrence Lu, Fiona Thistlethwaite

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002446; DOI: 10.1136/jitc-2021-002446
CX-072 (pacmilimab), a Probody^® PD-L1 inhibitor, in advanced or recurrent solid tumors (PROCLAIM-CX-072): an open-label dose-finding and first-in-human study
Aung Naing, Fiona Thistlethwaite, Elisabeth G.E. De Vries, Ferry A.L.M. Eskens, Nataliya Uboha, Patrick A. Ott, Patricia LoRusso, Javier Garcia-Corbacho, Valentina Boni, Johanna Bendell, Karen A. Autio, Manreet Randhawa, Greg Durm, Marta Gil-Martin, Mark Stroh, Alison L. Hannah, Hendrik-Tobias Arkenau, Alexander Spira

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002447; DOI: 10.1136/jitc-2021-002447
First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas
Sarina A Piha-Paul, Ravit Geva, Tira J Tan, Darren WT Lim, Cinta Hierro, Toshikiko Doi, Osama Rahma, Alexander Lesokhin, Jason John Luke, Javier Otero, Lisa Nardi, Angad Singh, Alexandros Xyrafas, Xinhui Chen, Jennifer Mataraza, Philippe L Bedard

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002863; DOI: 10.1136/jitc-2021-002863
Dual PD-L1 and TGF-b blockade in patients with recurrent respiratory papillomatosis
Yvette Robbins, Jay Friedman, Paul E Clavijo, Cem Sievers, Ke Bai, Renee N Donahue, Jeffrey Schlom, Andrew Sinkoe, Houssein Abdul Sater, James L Gulley, Scott Norberg, Christian S Hinrichs, Clint Allen

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003113; DOI: 10.1136/jitc-2021-003113
GB1275, a first-in-class CD11b modulator: rationale for immunotherapeutic combinations in solid tumors
David G DeNardo, Anna Galkin, Jakob Dupont, Lei Zhou, Johanna Bendell

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003005; DOI: 10.1136/jitc-2021-003005
Safety and efficacy of the tumor-selective adenovirus enadenotucirev with or without paclitaxel in platinum-resistant ovarian cancer: a phase 1 clinical trial
Victor Moreno, Maria-Pilar Barretina-Ginesta, Jesús García-Donas, Gordon C Jayson, Patricia Roxburgh, Raúl Márquez Vázquez, Agnieszka Michael, Antonio Antón-Torres, Richard Brown, David Krige, Brian Champion, Iain McNeish

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003645; DOI: 10.1136/jitc-2021-003645
Targeting cancer testis antigens in synovial sarcoma
Geoffrey Mitchell, Seth M Pollack, Michael J Wagner

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002072; DOI: 10.1136/jitc-2020-002072
Safety and activity of the TGFβ receptor I kinase inhibitor galunisertib plus the anti-PD-L1 antibody durvalumab in metastatic pancreatic cancer
Davide Melisi, Do-Youn Oh, Antoine Hollebecque, Emiliano Calvo, Anna Varghese, Erkut Borazanci, Teresa Macarulla, Valeria Merz, Camilla Zecchetto, Yumin Zhao, Ivelina Gueorguieva, Michael Man, Leena Gandhi, Shawn T Estrem, Karim A Benhadji, Mark C Lanasa, Emin Avsar, Susan C Guba, Rocio Garcia-Carbonero

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002068; DOI: 10.1136/jitc-2020-002068
Predicting anti-PD-1 responders in malignant melanoma from the frequency of S100A9+ monocytes in the blood
Soudabeh Rad Pour, Yago Pico de Coaña, Xavier Martinez Demorentin, Jeroen Melief, Manjula Thimma, Maria Wolodarski, David Gomez-Cabrero, Johan Hansson, Rolf Kiessling, Jesper Tegner

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002171; DOI: 10.1136/jitc-2020-002171

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