Macrophages

SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response
Kranthi Kiran Kishore Tanagala, Joshua Morin-Baxter, Richard Carvajal, Maryum Cheema, Sunil Dubey, Hiroshi Nakagawa, Angela Yoon, Yi-Shing L Cheng, Alison Taylor, Jeffrey Nickerson, Akiva Mintz, Fatemeh Momen-Heravi

Journal for ImmunoTherapy of Cancer Dec 2022, 10 (12) e005088; DOI: 10.1136/jitc-2022-005088
Macrophage GSK3β-deficiency inhibits the progression of hepatocellular carcinoma and enhances the sensitivity of anti-PD1 immunotherapy
Guangshun Sun, Hanyuan Liu, Jie Zhao, Jinyu Zhang, Tian Huang, Guoqiang Sun, Siqi Zhao, Zihao Zhang, Hengsong Cao, Dawei Rong, Xiangyi Kong, Qinghua Ji, Li Liu, Xuehao Wang, Weiwei Tang, Yongxiang Xia

Journal for ImmunoTherapy of Cancer Dec 2022, 10 (12) e005655; DOI: 10.1136/jitc-2022-005655
TIGIT blockade repolarizes AML-associated TIGIT⁺ M2 macrophages to an M1 phenotype and increases CD47-mediated phagocytosis
Franziska Brauneck, Brit Fischer, Marius Witt, Jana Muschhammer, Jennyfer Oelrich, Pedro Henrique da Costa Avelar, Sophia Tsoka, Lars Bullinger, Elisa Seubert, Daniel J Smit, Carsten Bokemeyer, Christin Ackermann, Jasmin Wellbrock, Friedrich Haag, Walter Fiedler

Journal for ImmunoTherapy of Cancer Dec 2022, 10 (12) e004794; DOI: 10.1136/jitc-2022-004794
Targeting tumor-associated macrophages for successful immunotherapy of ovarian carcinoma
Iva Truxova, David Cibula, Radek Spisek, Jitka Fucikova

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005968; DOI: 10.1136/jitc-2022-005968
Downregulation of phosphoserine phosphatase potentiates tumor immune environments to enhance immune checkpoint blockade therapy
Zhi-Peng Peng, Xing-Chen Liu, Yong-Hao Ruan, Da Jiang, Ai-Qi Huang, Wan-Ru Ning, Ze-Zhou Jiang, Limin Zheng, Yan Wu

Journal for ImmunoTherapy of Cancer Feb 2023, 11 (2) e005986; DOI: 10.1136/jitc-2022-005986
Antitumor immune effects of preoperative sitravatinib and nivolumab in oral cavity cancer: SNOW window-of-opportunity study
Marc Oliva, Douglas Chepeha, Daniel V Araujo, J. Javier Diaz-Mejia, Peter Olson, Amy Prawira, Anna Spreafico, Scott V Bratman, Tina Shek, John de Almeida, Aaron R Hansen, Andrew Hope, David Goldstein, Ilan Weinreb, Stephen Smith, Bayardo Perez-Ordoñez, Jonathan Irish, Dax Torti, Jeffrey P. Bruce, Ben X. Wang, Anthony Fortuna, Trevor J. Pugh, Hirak Der-Torossian, Ronald Shazer, Nickolas Attanasio, Qingyan Au, Antony Tin, Jordan Feeney, Himanshu Sethi, Alexey Aleshin, Isan Chen, Lillian Siu

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003476; DOI: 10.1136/jitc-2021-003476
Dual oxidase 1 limits the IFNγ-associated antitumor effect of macrophages
Lydia Meziani, Marine Gerbé de Thoré, Pauline Hamon, Sophie Bockel, Ruy A Louzada, Céline Clemenson, Raphaël Corre, Winchygn Liu, Corinne Dupuy, Michele Mondini, Eric Deutsch

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000622; DOI: 10.1136/jitc-2020-000622
Activation of MAT2A-RIP1 signaling axis reprograms monocytes in gastric cancer
Yan Zhang, Hui Yang, Jun Zhao, Ping Wan, Ye Hu, Kun Lv, YiRen Hu, Xi Yang, Mingzhe Ma

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001364; DOI: 10.1136/jitc-2020-001364
CXCL9-expressing tumor-associated macrophages: new players in the fight against cancer
Paola Marie Marcovecchio, Graham Thomas, Shahram Salek-Ardakani

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e002045; DOI: 10.1136/jitc-2020-002045
Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance
Han-Ying Cheng, Chia-Hsin Hsieh, Po-Han Lin, Yu-Tung Chen, Dennis Shin-Shian Hsu, Shyh-Kuan Tai, Pen-Yuan Chu, Muh-Hwa Yang

Journal for ImmunoTherapy of Cancer Aug 2022, 10 (8) e004832; DOI: 10.1136/jitc-2022-004832

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