Melanoma

Incidence of thromboembolism in patients with melanoma on immune checkpoint inhibitor therapy and its adverse association with survival
Tamara A Sussman, Hong Li, Brian Hobbs, Pauline Funchain, Keith R McCrae, Alok A Khorana

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001719; DOI: 10.1136/jitc-2020-001719
Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy
Anastasia Prokopi, Christoph H Tripp, Bart Tummers, Florian Hornsteiner, Sarah Spoeck, Jeremy Chase Crawford, Derek R Clements, Mirjana Efremova, Katharina Hutter, Lydia Bellmann, Giuseppe Cappellano, Bruno L Cadilha, Sebastian Kobold, Louis Boon, Daniela Ortner, Zlatko Trajanoski, Suzie Chen, Tanja D de Gruijl, Juliana Idoyaga, Douglas R Green, Patrizia Stoitzner

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e000832; DOI: 10.1136/jitc-2020-000832
Skin immunization for effective treatment of multifocal melanoma refractory to PD1 blockade and Braf inhibitors
Xingxing Hao, Louis D Falo III, Guo Chen, Jiying Zhang, Cara D Carey, Walter J Storkus, Louis D Falo Jr, Zhaoyang You

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001179; DOI: 10.1136/jitc-2020-001179
KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma
Pier Francesco Ferrucci, Anna Maria Di Giacomo, Michele Del Vecchio, Victoria Atkinson, Henrik Schmidt, Jacob Schachter, Paola Queirolo, Georgina V Long, Rosalie Stephens, Inge Marie Svane, Michal Lotem, Mahmoud Abu-Amna, Eduard Gasal, Razi Ghori, Scott J Diede, Elizabeth S Croydon, Antoni Ribas, Paolo Antonio Ascierto

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001806; DOI: 10.1136/jitc-2020-001806
Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy
Roberta Turiello, Mariaelena Capone, Diana Giannarelli, Elva Morretta, Maria Chiara Monti, Gabriele Madonna, Domenico Mallardo, Lucia Festino, Rosa Azzaro, Mitchell P Levesque, Laurence Imhof, Benjamin Weide, Teresa Amaral, Marc Chevrier, Antje Sucker, Piotr Rutkowski, Dirk Schadendorf, Celeste Lebbe, Jason John Luke, Kilian Wistuba-Hamprecht, Reinhard Dummer, Aldo Pinto, Silvana Morello, Paolo A Ascierto

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001689; DOI: 10.1136/jitc-2020-001689
Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer
Daan P Hurkmans, Els M E Verdegaal, Sabrina A Hogan, Rik de Wijn, Lies Hovestad, Dianne M A van den Heuvel, Rob Ruijtenbeek, Marij J P Welters, Mandy van Brakel, Edwin A Basak, Herbert M Pinedo, Cor H J Lamers, Harmen J G van de Werken, John P Groten, Reno Debets, Mitchell P Levesque, Reinhard Dummer, Ellen Kapiteijn, Ron H J Mathijssen, Joachim G J V Aerts, Sjoerd H van der Burg

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001607; DOI: 10.1136/jitc-2020-001607
Immune-mediated ototoxicity associated with immune checkpoint inhibitors in patients with melanoma
Samuel Rosner, Yuri Agrawal, Daniel Q Sun, Nafi Aygun, Megan D Schollenberger, Evan Lipson, Jarushka Naidoo

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001675; DOI: 10.1136/jitc-2020-001675
Mobilization of pre-existing polyclonal T cells specific to neoantigens but not self-antigens during treatment of a patient with melanoma with bempegaldesleukin and nivolumab
Joshua R Veatch, Naina Singhi, Brenda Jesernig, Kelly G Paulson, Jonathan Zalevsky, Ernesto Iacucci, Scott S Tykodi, Stanley R Riddell

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001591; DOI: 10.1136/jitc-2020-001591
A20 regulates the therapeutic effect of anti-PD-1 immunotherapy in melanoma
Weinan Guo, Jinyuan Ma, Sen Guo, Huina Wang, Sijia Wang, Qiong Shi, Lin Liu, Tao Zhao, Fengfan Yang, Shuyang Chen, Jianru Chen, Jianhong Zhao, Chen Yu, Xiuli Yi, Yuqi Yang, Jingjing Ma, Qingrong Ni, Guannan Zhu, Tianwen Gao, Chunying Li

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001866; DOI: 10.1136/jitc-2020-001866
Comprehensive analysis of cutaneous and uveal melanoma liver metastases
Esmee P Hoefsmit, Elisa A Rozeman, Trieu My Van, Petros Dimitriadis, Oscar Krijgsman, Jordan W Conway, Ines Pires da Silva, Jacqueline E van der Wal, Steven L C Ketelaars, Kaspar Bresser, Annegien Broeks, Ron M Kerkhoven, Jason W Reeves, Sarah Warren, Pia Kvistborg, Richard A Scolyer, Ellen W Kapiteijn, Daniel S Peeper, Georgina V Long, Ton N M Schumacher, Christian U Blank

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001501; DOI: 10.1136/jitc-2020-001501

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