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Bispecific antibody-mediated redirection of NKG2D-CAR natural killer cells facilitates dual targeting and enhances antitumor activity
Congcong Zhang, Jasmin Röder, Anne Scherer, Malena Bodden, Jordi Pfeifer Serrahima, Anita Bhatti, Anja Waldmann, Nina Müller, Pranav Oberoi, Winfried S Wels

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002980; DOI: 10.1136/jitc-2021-002980
Targeting human leukocyte antigen G with chimeric antigen receptors of natural killer cells convert immunosuppression to ablate solid tumors
Chia-Ing Jan, Shi-Wei Huang, Peter Canoll, Jeffrey N Bruce, Yu-Chuan Lin, Chih-Ming Pan, Hsin-Man Lu, Shao-Chih Chiu, Der-Yang Cho

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e003050; DOI: 10.1136/jitc-2021-003050
TGFβ drives NK cell metabolic dysfunction in human metastatic breast cancer
Karen Slattery, Elena Woods, Vanessa Zaiatz-Bittencourt, Sam Marks, Sonya Chew, Michael Conroy, Caitriona Goggin, Colm MacEochagain, John Kennedy, Sophie Lucas, David K Finlay, Clair M Gardiner

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e002044; DOI: 10.1136/jitc-2020-002044
STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation
Takashi Nakamura, Takanori Sato, Rikito Endo, Shun Sasaki, Naomichi Takahashi, Yusuke Sato, Mamoru Hyodo, Yoshihiro Hayakawa, Hideyoshi Harashima

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002852; DOI: 10.1136/jitc-2021-002852
Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2⁺ pediatric solid tumors and in vivo survival of xenografted immunodeficient NSG mice
Yaya Chu, Gaurav Nayyar, Susiyan Jiang, Jeremy M. Rosenblum, Patrick Soon-Shiong, Jeffrey T Safrit, Dean A. Lee, Mitchell S. Cairo

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002267; DOI: 10.1136/jitc-2020-002267
NK cells enhance CAR-T cell antitumor efficacy by enhancing immune/tumor cells cluster formation and improving CAR-T cell fitness
Mireia Bachiller, Lorena Perez-Amill, Anthony Matthew Battram, Sebastian Ciro Carné, Amer Najjar, Els Verhoeyen, Manel Juan, Alvaro Urbano-Ispizua, Beatriz Martin-Antonio

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002866; DOI: 10.1136/jitc-2021-002866
LINC01140 promotes the progression and tumor immune escape in lung cancer by sponging multiple microRNAs
Rongmu Xia, Guojun Geng, Xiuyi Yu, Zhong Xu, Jing Guo, Hongming Liu, Ning Li, Ziyan Li, Yingli Li, Xiaofang Dai, Qicong Luo, Jie Jiang, Yanjun Mi

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002746; DOI: 10.1136/jitc-2021-002746
Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities
Ilias Christodoulou, Won Jin Ho, Andrew Marple, Jonas W Ravich, Ada Tam, Ruyan Rahnama, Adam Fearnow, Cambrynne Rietberg, Sean Yanik, Elena E Solomou, Ravi Varadhan, Michael A Koldobskiy, Challice L Bonifant

Journal for ImmunoTherapy of Cancer Dec 2021, 9 (12) e003894; DOI: 10.1136/jitc-2021-003894
Oncolytic parainfluenza virus combines with NK cells to mediate killing of infected and non-infected lung cancer cells within 3D spheroids: role of type I and type III interferon signaling
Namita Varudkar, Jeremiah L Oyer, Alicja Copik, Griffith D Parks

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002373; DOI: 10.1136/jitc-2021-002373
Clinical and immunologic impact of short-course enzalutamide alone and with immunotherapy in non-metastatic castration sensitive prostate cancer
Ravi A Madan, Fatima Karzai, Renee N Donahue, Munjid Al-Harthy, Marijo Bilusic, Inger I Rosner, Harpreet Singh, Philip M Arlen, Marc R Theoret, Jennifer L Marté, Lisa Cordes, Anna Couvillon, Amy Hankin, Moniquea Williams, Helen Owens, Sarah E Lochrin, Cindy H Chau, Seth Steinberg, William Douglas Figg, William Dahut, Jeffrey Schlom, James L Gulley

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001556; DOI: 10.1136/jitc-2020-001556

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