radioimmunotherapy

Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma
Rom Leidner, Marka Crittenden, Kristina Young, Hong Xiao, Yaping Wu, Marcus A Couey, Ashish A Patel, Allen C Cheng, Amber L Watters, Carlo Bifulco, George Morris, Lessli Rushforth, Shorin Nemeth, Walter J Urba, Michael Gough, R Bryan Bell

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002485; DOI: 10.1136/jitc-2021-002485
In situ delivery of iPSC-derived dendritic cells with local radiotherapy generates systemic antitumor immunity and potentiates PD-L1 blockade in preclinical poorly immunogenic tumor models
Takaaki Oba, Kenichi Makino, Ryutaro Kajihara, Toshihiro Yokoi, Ryoko Araki, Masumi Abe, Hans Minderman, Alfred E Chang, Kunle Odunsi, Fumito Ito

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002432; DOI: 10.1136/jitc-2021-002432
Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies
Lambros Tselikas, Thierry de Baere, Thomas Isoardo, Sandrine Susini, Karine Ser-Le Roux, Mélanie Polrot, Julien Adam, Mathieu Rouanne, Laurence Zitvogel, Laurence Moine, Fréderic Deschamps, Aurélien Marabelle

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000579; DOI: 10.1136/jitc-2020-000579
Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis
Michael W Knitz, Thomas E Bickett, Laurel B Darragh, Ayman J Oweida, Shilpa Bhatia, Benjamin Van Court, Shiv Bhuvane, Miles Piper, Jacob Gadwa, Adam C Mueller, Diemmy Nguyen, Varuna Nangia, Douglas G Osborne, Xiyuan Bai, Sarah E Ferrara, Mary-Keara Boss, Andrew Goodspeed, Matthew A Burchill, Beth A Jirón Tamburini, Edward D Chan, Curtis R Pickering, Eric T Clambey, Sana D Karam

Journal for ImmunoTherapy of Cancer Apr 2021, 9 (4) e001955; DOI: 10.1136/jitc-2020-001955
Durvalumab and tremelimumab with or without stereotactic body radiation therapy in relapsed small cell lung cancer: a randomized phase II study
Suchita Pakkala, Kristin Higgins, Zhengjia Chen, Gabriel Sica, Conor Steuer, Chao Zhang, Guojing Zhang, Shuhua Wang, Mohammad S Hossain, Bassel Nazha, Tyler Beardslee, Fadlo R Khuri, Walter Curran, Sagar Lonial, Edmund K Waller, Suresh Ramalingam, Taofeek K Owonikoko

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001302; DOI: 10.1136/jitc-2020-001302
Radiomics to predict outcomes and abscopal response of patients with cancer treated with immunotherapy combined with radiotherapy using a validated signature of CD8 cells
Roger Sun, Nora Sundahl, Markus Hecht, Florian Putz, Andrea Lancia, Angela Rouyar, Marina Milic, Alexandre Carré, Enzo Battistella, Emilie Alvarez Andres, Stéphane Niyoteka, Edouard Romano, Guillaume Louvel, Jérôme Durand-Labrunie, Sophie Bockel, Rastilav Bahleda, Charlotte Robert, Celine Boutros, Maria Vakalopoulou, Nikos Paragios, Benjamin Frey, Jean-Charles Soria, Christophe Massard, Charles Ferté, Rainer Fietkau, Piet Ost, Udo Gaipl, Eric Deutsch

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (2) e001429; DOI: 10.1136/jitc-2020-001429
Low-dose radiation treatment enhances systemic antitumor immune responses by overcoming the inhibitory stroma
Hampartsoum B Barsoumian, Rishab Ramapriyan, Ahmed I Younes, Mauricio S Caetano, Hari Menon, Nathan I Comeaux, Taylor R Cushman, Jonathan E Schoenhals, Alexandra P Cadena, Timothy P Reilly, Dawei Chen, Fatemeh Masrorpour, Ailin Li, David S Hong, Adi Diab, Quynh-Nhu Nguyen, Isabella Glitza, Renata Ferrarotto, Stephen G Chun, Maria Angelica Cortez, James Welsh

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e000537; DOI: 10.1136/jitc-2020-000537
Pembrolizumab with or without radiation therapy for metastatic non-small cell lung cancer: a randomized phase I/II trial
James Welsh, Hari Menon, Dawei Chen, Vivek Verma, Chad Tang, Mehmet Altan, Kenneth Hess, Patricia de Groot, Quynh-Nhu Nguyen, Rejani Varghese, Nathan I Comeaux, George Simon, Ferdinandos Skoulidis, Joe Y Chang, Vasiliki Papdimitrakopoulou, Steven H Lin, John V Heymach

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e001001; DOI: 10.1136/jitc-2020-001001
Safety and clinical activity of intratumoral MEDI9197 alone and in combination with durvalumab and/or palliative radiation therapy in patients with advanced solid tumors
Lillian Siu, Joshua Brody, Shilpa Gupta, Aurélien Marabelle, Antonio Jimeno, Pamela Munster, Juneko Grilley-Olson, Alain H Rook, Antoine Hollebecque, Rebecca K S Wong, James W Welsh, Yuling Wu, Christopher Morehouse, Oday Hamid, Farzana Walcott, Zachary A Cooper, Rakesh Kumar, Charles Ferté, David S Hong

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e001095; DOI: 10.1136/jitc-2020-001095
Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/ durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8
Markus Hecht, Antoniu Oreste Gostian, Markus Eckstein, Sandra Rutzner, Jens von der Grün, Thomas Illmer, Matthias G Hautmann, Gunther Klautke, Simon Laban, Thomas Brunner, Axel Hinke, Ina Becker, Benjamin Frey, Sabine Semrau, Carol I Geppert, Arndt Hartmann, Panagiotis Balermpas, Wilfried Budach, Udo S Gaipl, Heinrich Iro, Rainer Fietkau

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e001378; DOI: 10.1136/jitc-2020-001378

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