tumor biomarkers

Soluble HLA peptidome of pleural effusions is a valuable source for tumor antigens
Sofia Khazan-Kost, Gal Cafri, Dganit Melamed Kadosh, Navit Mooshayef, Sumit Chatterji, Dan Dominissini, Sigal Manor, Bracha Zisser, Limor Broday, Efrosiniia Talalai, Anat Shemer, Oranit Zadok, Efrat Ofek, Amir Onn, Arie Admon, Michael Peled

Journal for ImmunoTherapy of Cancer May 2022, 10 (5) e003733; DOI: 10.1136/jitc-2021-003733
Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developing a prognostic multivariate model
Koichi Azuma, Huihui Xiang, Tomoyuki Tagami, Rika Kasajima, Yumiko Kato, Sachise Karakawa, Shinya Kikuchi, Akira Imaizumi, Norikazu Matsuo, Hidenobu Ishii, Takaaki Tokito, Akihiko Kawahara, Kenta Murotani, Tetsuro Sasada, Yohei Miyagi, Tomoaki Hoshino

Journal for ImmunoTherapy of Cancer May 2022, 10 (5) e004420; DOI: 10.1136/jitc-2021-004420
High levels of chromosomal aberrations negatively associate with benefit to checkpoint inhibition in NSCLC
Joan Frigola, Caterina Carbonell, Patricia Irazno, Nuria Pardo, Ana Callejo, Susana Cedres, Alex Martinez-Marti, Alejandro Navarro, Mireia Soleda, Jose Jimenez, Javier Hernandez-Losa, Ana Vivancos, Enriqueta Felip, Ramon Amat

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004197; DOI: 10.1136/jitc-2021-004197
Patients with HIV-associated cancers have evidence of increased T cell dysfunction and exhaustion prior to cancer diagnosis
Omkar Chaudhary, Diane Trotta, Kaicheng Wang, Xun Wang, Xiuping Chu, Chip Bradley, Jason Okulicz, Ryan C Maves, Karl Kronmann, Christina M Schofield, Jason M Blaylock, Yanhong Deng, Kurt A Schalper, Susan M Kaech, Brian Agan, Anuradha Ganesan, Brinda Emu

Journal for ImmunoTherapy of Cancer Apr 2022, 10 (4) e004564; DOI: 10.1136/jitc-2022-004564
Effect of neoadjuvant chemotherapy on the immune microenvironment in gastric cancer as determined by multiplex immunofluorescence and T cell receptor repertoire analysis
Xiaofang Xing, Jinyao Shi, Yongning Jia, Yunsheng Dou, Zhongwu Li, Bin Dong, Ting Guo, Xiaojing Cheng, Xiaomei Li, Hong Du, Ying Hu, Shuqin Jia, Jian Zhang, Ziyu Li, Jiafu Ji

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003984; DOI: 10.1136/jitc-2021-003984
Immunosuppressive tumor-associated macrophages expressing interlukin-10 conferred poor prognosis and therapeutic vulnerability in patients with muscle-invasive bladder cancer
Yijia Xu, Han Zeng, Kaifeng Jin, Zhaopei Liu, Yu Zhu, Le Xu, Zewei Wang, Yuan Chang, Jiejie Xu

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003416; DOI: 10.1136/jitc-2021-003416
Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma
Robert J Motzer, Toni K Choueiri, David F McDermott, Thomas Powles, Yann-Alexandre Vano, Saurabh Gupta, Jin Yao, Celine Han, Ron Ammar, Simon Papillon-Cavanagh, Shruti S Saggi, M Brent McHenry, Petra Ross-Macdonald, Megan Wind-Rotolo

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004316; DOI: 10.1136/jitc-2021-004316
Cancer cell-intrinsic resistance to BiTE therapy is mediated by loss of CD58 costimulation and modulation of the extrinsic apoptotic pathway
Ye Shen, Jason S Eng, Flordeliza Fajardo, Lingming Liang, Cong Li, Patrick Collins, Donato Tedesco, Olivier Nolan-Stevaux

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e004348; DOI: 10.1136/jitc-2021-004348
Novel imaging biomarkers predict outcomes in stage III unresectable non-small cell lung cancer treated with chemoradiation and durvalumab
Khalid Jazieh, Mohammadhadi Khorrami, Anas Saad, Mohamed Gad, Amit Gupta, Pradnya Patil, Vidya Sankar Viswanathan, Prabhakar Rajiah, Charles J Nock, Michael Gilkey, Pingfu Fu, Nathan A Pennell, Anant Madabhushi

Journal for ImmunoTherapy of Cancer Mar 2022, 10 (3) e003778; DOI: 10.1136/jitc-2021-003778
Influence of tumor mutational burden, inflammatory gene expression profile, and PD-L1 expression on response to pembrolizumab in head and neck squamous cell carcinoma
Robert I Haddad, Tanguy Y Seiwert, Laura Q M Chow, Shilpa Gupta, Jared Weiss, Iris Gluck, Joseph P Eder, Barbara Burtness, Makoto Tahara, Bhumsuk Keam, Hyunseok Kang, Kei Muro, Andrew Albright, Robin Mogg, Mark Ayers, Lingkang Huang, Jared Lunceford, Razvan Cristescu, Jonathan Cheng, Ranee Mehra

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003026; DOI: 10.1136/jitc-2021-003026

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