tumor biomarkers

Use of plasma ctDNA as a potential biomarker for longitudinal monitoring of a patient with metastatic high-risk upper tract urothelial carcinoma receiving pembrolizumab and personalized neoepitope-derived multipeptide vaccinations: a case report
Carolin Blumendeller, Julius Boehme, Maximilian Frick, Martin Schulze, Antje Rinckleb, Christina Kyzirakos, Simone Kayser, Maria Kopp, Sabine Kelkenberg, Natalia Pieper, Oliver Bartsch, Dirk Hadaschick, Florian Battke, Arnulf Stenzl, Saskia Biskup

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001406; DOI: 10.1136/jitc-2020-001406
Serum CD73 is a prognostic factor in patients with metastatic melanoma and is associated with response to anti-PD-1 therapy
Roberta Turiello, Mariaelena Capone, Diana Giannarelli, Elva Morretta, Maria Chiara Monti, Gabriele Madonna, Domenico Mallardo, Lucia Festino, Rosa Azzaro, Mitchell P Levesque, Laurence Imhof, Benjamin Weide, Teresa Amaral, Marc Chevrier, Antje Sucker, Piotr Rutkowski, Dirk Schadendorf, Celeste Lebbe, Jason John Luke, Kilian Wistuba-Hamprecht, Reinhard Dummer, Aldo Pinto, Silvana Morello, Paolo A Ascierto

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001689; DOI: 10.1136/jitc-2020-001689
Glucose-6-phosphate dehydrogenase correlates with tumor immune activity and programmed death ligand-1 expression in Merkel cell carcinoma
Motoki Nakamura, Kotaro Nagase, Maki Yoshimitsu, Tetsuya Magara, Yuka Nojiri, Hiroshi Kato, Tadahiro Kobayashi, Yukiko Teramoto, Masahito Yasuda, Hidefumi Wada, Toshiyuki Ozawa, Yukie Umemori, Dai Ogata, Akimichi Morita

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001679; DOI: 10.1136/jitc-2020-001679
Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume II—practical challenges
Alessandra Cesano, Michael A Cannarile, Sacha Gnjatic, Bruno Gomes, Justin Guinney, Vaios Karanikas, Mohan Karkada, John M Kirkwood, Beatrix Kotlan, Giuseppe V Masucci, Els Meeusen, Anne Monette, Aung Naing, Vésteinn Thorsson, Nicholas Tschernia, Ena Wang, Daniel K Wells, Timothy L Wyant, Sergio Rutella

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001472; DOI: 10.1136/jitc-2020-001472
Mitochondrial Lon-induced mtDNA leakage contributes to PD-L1–mediated immunoescape via STING-IFN signaling and extracellular vesicles
An Ning Cheng, Li-Chun Cheng, Cheng-Liang Kuo, Yu Kang Lo, Han-Yu Chou, Chung-Hsing Chen, Yi-Hao Wang, Tsung-Hsien Chuang, Shih-Jung Cheng, Alan Yueh-Luen Lee

Journal for ImmunoTherapy of Cancer Dec 2020, 8 (2) e001372; DOI: 10.1136/jitc-2020-001372
PODO447: a novel antibody to a tumor-restricted epitope on the cancer antigen podocalyxin
Diana Canals Hernaez, Michael R Hughes, Pamela Dean, Peter Bergqvist, Ismael Samudio, Ola Blixt, Katharina Wiedemeyer, Yicong Li, Chris Bond, Eric Cruz, Martin Köbel, Blake Gilks, Calvin D Roskelley, Kelly M McNagny

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (2) e001128; DOI: 10.1136/jitc-2020-001128
Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy
Yong Qin, Kathryn Bollin, Mariana Petaccia de Macedo, Fernando Carapeto, Kevin B Kim, Jason Roszik, Khalida M Wani, Alexandre Reuben, Sujan T Reddy, Michelle D Williams, Michael T Tetzlaff, Wei-Lien Wang, Dan S Gombos, Bita Esmaeli, Alexander J Lazar, Patrick Hwu, Sapna P Patel

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (2) e000960; DOI: 10.1136/jitc-2020-000960
Radiomics to predict outcomes and abscopal response of patients with cancer treated with immunotherapy combined with radiotherapy using a validated signature of CD8 cells
Roger Sun, Nora Sundahl, Markus Hecht, Florian Putz, Andrea Lancia, Angela Rouyar, Marina Milic, Alexandre Carré, Enzo Battistella, Emilie Alvarez Andres, Stéphane Niyoteka, Edouard Romano, Guillaume Louvel, Jérôme Durand-Labrunie, Sophie Bockel, Rastilav Bahleda, Charlotte Robert, Celine Boutros, Maria Vakalopoulou, Nikos Paragios, Benjamin Frey, Jean-Charles Soria, Christophe Massard, Charles Ferté, Rainer Fietkau, Piet Ost, Udo Gaipl, Eric Deutsch

Journal for ImmunoTherapy of Cancer Nov 2020, 8 (2) e001429; DOI: 10.1136/jitc-2020-001429
Phase Ib study of anti-CSF-1R antibody emactuzumab in combination with CD40 agonist selicrelumab in advanced solid tumor patients
Jean-Pascal Machiels, Carlos Gomez-Roca, Jean-Marie Michot, Dmitriy Zamarin, Tara Mitchell, Gaetan Catala, Lauriane Eberst, Wolfgang Jacob, Anna-Maria Jegg, Michael A Cannarile, Carl Watson, Galina Babitzki, Konstanty Korski, Irina Klaman, Priscila Teixeira, Sabine Hoves, Carola Ries, Georgina Meneses-Lorente, Francesca Michielin, Randolph Christen, Dominik Rüttinger, Martin Weisser, Jean-Pierre Delord, Philippe Cassier

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e001153; DOI: 10.1136/jitc-2020-001153
Clinical, FDG-PET and molecular markers of immune checkpoint inhibitor response in patients with metastatic Merkel cell carcinoma
Alison M Weppler, Andrew Pattison, Prachi Bhave, Paolo De Ieso, Jeanette Raleigh, Athena Hatzimihalis, Anthony J Gill, Shiva Balachander, Jason Callahan, Margaret Chua, George Au-Yeung, Grant A McArthur, Rodney J Hicks, Richard W Tothill, Shahneen Sandhu

Journal for ImmunoTherapy of Cancer Oct 2020, 8 (2) e000700; DOI: 10.1136/jitc-2020-000700

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