tumor biomarkers

TERT promoter mutations and other prognostic factors in patients with advanced urothelial carcinoma treated with an immune checkpoint inhibitor
Ivan de Kouchkovsky, Li Zhang, Errol J Philip, Francis Wright, Daniel M Kim, Divya Natesan, Daniel Kwon, Hansen Ho, Son Ho, Emily Chan, Sima P Porten, Anthony C Wong, Arpita Desai, Franklin W Huang, Jonathan Chou, David Y Oh, Raj S Pruthi, Lawrence Fong, Eric J Small, Terence W Friedlander, Vadim Koshkin

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002127; DOI: 10.1136/jitc-2020-002127
Pan-cancer landscape of CD274 (PD-L1) copy number changes in 244 584 patient samples and the correlation with PD-L1 protein expression
Richard S.P. Huang, Karthikeyan Murugesan, Meagan Montesion, Dean C. Pavlick, Douglas A. Mata, Matthew C. Hiemenz, Brennan Decker, Garrett Frampton, Lee A. Albacker, Jeffrey S. Ross

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002680; DOI: 10.1136/jitc-2021-002680
Cell-free DNA copy number variations predict efficacy of immune checkpoint inhibitor-based therapy in hepatobiliary cancers
Xu Yang, Ying Hu, Keyan Yang, Dongxu Wang, Jianzhen Lin, Junyu Long, Fucun Xie, Jinzhu Mao, Jin Bian, Mei Guan, Jie Pan, Li Huo, Ke Hu, Xiaobo Yang, Yilei Mao, Xinting Sang, Jiao Zhang, Xi Wang, Henghui Zhang, Haitao Zhao

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e001942; DOI: 10.1136/jitc-2020-001942
Tumor mutational burden assessment in non-small-cell lung cancer samples: results from the TMB² harmonization project comparing three NGS panels
Javier Ramos-Paradas, Susana Hernández-Prieto, David Lora, Elena Sanchez, Aranzazu Rosado, Tamara Caniego-Casas, Nuria Carrizo, Ana Belén Enguita, María Teresa Muñoz-Jimenez, Borja Rodriguez, Urbicio Perez-Gonzalez, David Gómez-Sánchez, Irene Ferrer, Santiago Ponce Aix, Ángel Nuñez Buiza, Pilar Garrido, José Palacios, Fernando Lopez-Rios, Eva M Garrido-Martin, Luis Paz-Ares

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e001904; DOI: 10.1136/jitc-2020-001904
Prognostic impact of early tumor shrinkage and depth of response in patients with microsatellite instability-high metastatic colorectal cancer receiving immune checkpoint inhibitors
Giovanni Fucà, Francesca Corti, Margherita Ambrosini, Rossana Intini, Massimiliano Salati, Elisabetta Fenocchio, Paolo Manca, Chiara Manai, Francesca Daniel, Alessandra Raimondi, Federica Morano, Salvatore Corallo, Michele Prisciandaro, Andrea Spallanzani, Virginia Quarà, Carmen Belli, Marta Vaiani, Giuseppe Curigliano, Chiara Cremolini, Filippo De Braud, Maria Di Bartolomeo, Vittorina Zagonel, Sara Lonardi, Filippo Pietrantonio

Journal for ImmunoTherapy of Cancer Apr 2021, 9 (4) e002501; DOI: 10.1136/jitc-2021-002501
Multiomics analysis reveals a distinct response mechanism in multiple primary lung adenocarcinoma after neoadjuvant immunotherapy
Chao Zhang, Kai Yin, Si-Yang Liu, Li-Xu Yan, Jian Su, Yi-Long Wu, Xu-Chao Zhang, Wen-Zhao Zhong, Xue-Ning Yang

Journal for ImmunoTherapy of Cancer Apr 2021, 9 (4) e002312; DOI: 10.1136/jitc-2020-002312
Multiparametric flow cytometry highlights B7-H3 as a novel diagnostic/therapeutic target in GD2neg/low neuroblastoma variants
Alessandra Dondero, Martina Morini, Davide Cangelosi, Katia Mazzocco, Martina Serra, Grazia Maria Spaggiari, Gianluca Rotta, Annalisa Tondo, Franco Locatelli, Aurora Castellano, Francesca Scuderi, Angela Rita Sementa, Alessandra Eva, Massimo Conte, Alberto Garaventa, Cristina Bottino, Roberta Castriconi

Journal for ImmunoTherapy of Cancer Apr 2021, 9 (4) e002293; DOI: 10.1136/jitc-2020-002293
Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma
Yuxiang Ma, Xi Chen, Ao Wang, Hongyun Zhao, Qingguang Lin, Hua Bao, Yang Zhang, Shaodong Hong, Wanxiangfu Tang, Yan Huang, Yunpeng Yang, Xue Wu, Yang Shao, Wenfeng Fang, Li Zhang

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e002014; DOI: 10.1136/jitc-2020-002014
Plasma cell marker, immunoglobulin J polypeptide, predicts early disease-specific mortality in HPV+ HNSCC
Shanying Gui, W Quinn O'Neill, Theodoros N Teknos, Quintin Pan

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001259; DOI: 10.1136/jitc-2020-001259
Anti-GD2 antibody dinutuximab inhibits triple-negative breast tumor growth by targeting GD2⁺ breast cancer stem-like cells
Stanley Ly, Vivek Anand, Fouad El-Dana, Khoa Nguyen, Yiming Cai, Shirong Cai, Helen Piwnica-Worms, Debasish Tripathy, Aysegul A Sahin, Michael Andreeff, Venkata Lokesh Battula

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001197; DOI: 10.1136/jitc-2020-001197

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