tumor escape

Neutrophils in the era of immune checkpoint blockade
Julien Faget, Solange Peters, Xavier Quantin, Etienne Meylan, Nathalie Bonnefoy

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002242; DOI: 10.1136/jitc-2020-002242
MYC suppresses STING-dependent innate immunity by transcriptionally upregulating DNMT1 in triple-negative breast cancer
Si-Yu Wu, Yi Xiao, Jin-Li Wei, Xiao-En Xu, Xi Jin, Xin Hu, Da-Qiang Li, Yi-Zhou Jiang, Zhi-Ming Shao

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002528; DOI: 10.1136/jitc-2021-002528
WDR5-H3K4me3 epigenetic axis regulates OPN expression to compensate PD-L1 function to promote pancreatic cancer immune escape
Chunwan Lu, Zhuoqi Liu, John D Klement, Dafeng Yang, Alyssa D Merting, Dakota Poschel, Thomas Albers, Jennifer L Waller, Huidong Shi, Kebin Liu

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002624; DOI: 10.1136/jitc-2021-002624
Overexpression of CD200 is a stem cell-specific mechanism of immune evasion in AML
Shelley Herbrich, Natalia Baran, Tianyu Cai, Connie Weng, Marisa J L Aitken, Sean M Post, Jared Henderson, Chunhua Shi, Ondrej Havranek, Guillame Richard-Carpentier, Guy Sauvageau, Keith Baggerly, Gheath Al-Atrash, R Eric Davis, Naval Daver, Dongxing Zha, Marina Konopleva

Journal for ImmunoTherapy of Cancer Jul 2021, 9 (7) e002968; DOI: 10.1136/jitc-2021-002968
THADA drives Golgi residency and upregulation of PD-L1 in cancer cells and provides promising target for immunotherapy
Chushu Li, Hao Chi, Shouyan Deng, Ke Xu, Huanbin Wang, Han Yao, Yungang Wang, Dawei Chen, Xun Guo, Jing-Yuan Fang, Fang He, Jie Xu

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e002443; DOI: 10.1136/jitc-2021-002443
Cystathionine β-synthase mediated PRRX2/IL-6/STAT3 inactivation suppresses Tregs infiltration and induces apoptosis to inhibit HCC carcinogenesis
Yu-Fu Zhou, Shu-Shu Song, Meng-Xin Tian, Zheng Tang, Han Wang, Yuan Fang, Wei-Feng Qu, Xi-Fei Jiang, Chen-Yang Tao, Run Huang, Pei-Yun Zhou, Shi-Guo Zhu, Jian Zhou, Jia Fan, Wei-Ren Liu, Ying-Hong Shi

Journal for ImmunoTherapy of Cancer Aug 2021, 9 (8) e003031; DOI: 10.1136/jitc-2021-003031
First immunotherapeutic CAR-T cells against the immune checkpoint protein HLA-G
François Anna, Elodie Bole-Richard, Joel LeMaoult, Marie Escande, Martin Lecomte, Jean-Marie Certoux, Philippe Souque, Francine Garnache, Olivier Adotevi, Pierre Langlade-Demoyen, Maria Loustau, Julien Caumartin

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001998; DOI: 10.1136/jitc-2020-001998
MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination
Xiaofang Wu, Marie Nelson, Mousumi Basu, Priya Srinivasan, Christopher Lazarski, Peng Zhang, Pan Zheng, Anthony David Sandler

Journal for ImmunoTherapy of Cancer Mar 2021, 9 (3) e001388; DOI: 10.1136/jitc-2020-001388
A tipping point in cancer-immune dynamics leads to divergent immunotherapy responses and hampers biomarker discovery
Jeroen H A Creemers, W Joost Lesterhuis, Niven Mehra, Winald R Gerritsen, Carl G Figdor, I Jolanda M de Vries, Johannes Textor

Journal for ImmunoTherapy of Cancer May 2021, 9 (5) e002032; DOI: 10.1136/jitc-2020-002032
Small cell transformation of non-small cell lung cancer on immune checkpoint inhibitors: uncommon or under-recognized?
Kartik Sehgal, Andreas Varkaris, Hollis Viray, Paul A VanderLaan, Deepa Rangachari, Daniel B Costa

Journal for ImmunoTherapy of Cancer Jun 2020, 8 (1) e000697; DOI: 10.1136/jitc-2020-000697

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