Tumor Infiltrate Lymphocyte

Immune status at pre-treatment impacts on progression-free survival of metastatic colorectal cancer patients treated with first-line chemotherapy
Kohei Tada, Shigehisa Kitano, Hirokazu Shoji, Takashi Nishimura, Yasuhiro Shimada, Kengo Nagashima, Yoshitaka Honma, Satoru Iwasa, Natsuko Okita, Atsuo Takashima, Ken Kato, Yasuhide Yamada, Naoyuki Katayama, Narikazu Boku, Tetsuya Hamaguchi, Yuji Heike

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P108; DOI: 10.1186/2051-1426-3-S2-P108
Personalized immunotherapy for non-small cell lung cancer through identification of tumor-specific mutations by next generation sequencing and adoptive transfer of tumor infiltrating lymphocytes that recognize neoantigens
Ken-ichi Hanada, Christopher Chow, Raul Gil Hoyos, Jared J Gartner, Todd D Prickett, Robert Somerville, Katherine Hogan, Paul F Robbins, Steven A Rosenberg, James C Yang

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P20; DOI: 10.1186/2051-1426-3-S2-P20
Durable complete response in a patient with metastatic melanoma following adoptive transfer of autologous T cells recognizing 10 mutated tumor antigens
Todd D Prickett, Jessica S Crystal, Jared J Gartner, Yao Xin, Pasetto Anna, Alena Gros, Yong-Chen Lu, Yong Li, Mona El-Gamil, Steven A Rosenberg, Paul Robbins

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) O4; DOI: 10.1186/2051-1426-3-S2-O4
A Phase I study to evaluate the safety and antitumor activity of durvalumab (MEDI4736) in combination with tremelimumab in patients with advanced solid tumors
Kyriakos P Papadopoulos, Frank Tsai, Omid Hamid, Feng Xiao, Keith E Steele, Marlon C Rebelatto, Paul B Robbins, Joyson J Karakunnel, Dominic W Lai, Amit Mahipal

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P165; DOI: 10.1186/2051-1426-3-S2-P165
Phase I study of patients with non-muscle invasive bladder cancer (NMIBC) treated with vesigenurtacel-L (HS-410) after Bacillus Calmette-Guérin (BCG)
Gary Steinberg, Neal Shore, Lawrence Karsh, James Bailen, Michael Woods, Taylor Schreiber, Melissa Price

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P447; DOI: 10.1186/2051-1426-3-S2-P447
Prognostic and biologic significance of high LCK expression in ovarian cancer
Amir Jazaeri, Cherie Paquette, Sarah M Kelting, Mark H Stoler, Qian Zhang, Melinda Yates, Caitlin Creasy, Chantale Bernatchez, Patrick Hwu

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P93; DOI: 10.1186/2051-1426-3-S2-P93
Level of PD-1 expression on CD8+ T cells influence prognosis and respond to PD-1 therapy in a murine model
Benjamin A Kansy, Raghvendra M Srivastava, Hyun-Bae Jie, Gulidanna Shayan, Yu Lei, Jing Li, William Gooding, Sven Brandau, Stephan Lang, Nicole Schmitt, Gordon J Freeman, David A Clump, Robert L Ferris

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P228; DOI: 10.1186/2051-1426-3-S2-P228
Anti-EGFR mAb cetuximab therapy increases T cell receptor (TCR) diversity in the peripheral blood and focuses TCR richness in the tumor microenvironment
Benjamin A Kansy, Yan Lin, Fei Ding, Sandra Poveda Gibson, Hyun-Bae Jie, Robert L Ferris

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P73; DOI: 10.1186/2051-1426-3-S2-P73
Modulating immunometabolism of tumor specific mouse and human lymphocytes to enhance T cell based therapy for cancer
Madhusudhanan Sukumar, Jie Liu, Shashank J Patel, Christopher A Klebanoff, Gautam Mehta, Rahul Roychoudhuri, Joseph Crompton, David Clever, Luca Gattinoni, Pawel Muranski, Toren Finkel, Nicholas Restifo

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P325; DOI: 10.1186/2051-1426-3-S2-P325
Single-cell motility and gene expression signature as predictors of the overall survival of act in melanoma patients
Melisa Martinez-Paniagua, Cara Haymaker, Jay R Adolacion, Laszlo Radvanyi, Patrick Hwu, Badrinath Roysam, Chantale Bernatchez, Navin Varadarajan

Journal for ImmunoTherapy of Cancer Dec 2015, 3 (Suppl 2) P33; DOI: 10.1186/2051-1426-3-S2-P33

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