Tumor Microenvironment

Guidelines for immunological analyses following focused ultrasound treatment
Frederic Padilla, Jessica Foley, Kelsie Timbie, Timothy N J Bullock, Natasha D Sheybani

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007455; DOI: 10.1136/jitc-2023-007455
Neuroblastoma: an ongoing cold front for cancer immunotherapy
Paul T Kennedy, Demetra Zannoupa, Meong Hi Son, Lekh N Dahal, John F Woolley

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007798; DOI: 10.1136/jitc-2023-007798
Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistance
Jamaal L James, Brandie C Taylor, Margaret L Axelrod, Xiaopeng Sun, Lindsey N Guerin, Paula I Gonzalez-Ericsson, Yu Wang, Violeta Sanchez, Catherine C Fahey, Melinda E Sanders, Yaomin Xu, Emily Hodges, Douglas B Johnson, Justin M Balko

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007736; DOI: 10.1136/jitc-2023-007736
Systemic infusion of TLR3-ligand and IFN-α in patients with breast cancer reprograms local tumor microenvironments for selective CTL influx
Shipra Gandhi, Mateusz Opyrchal, Melissa J Grimm, Ronald T Slomba, Kathleen M Kokolus, Agnieszka Witkiewicz, Kristopher Attwood, Adrienne Groman, Lauren Williams, Mary Lynne Tarquini, Paul K Wallace, Kah Teong Soh, Hans Minderman, Orla Maguire, Tracey L O’Connor, Amy P Early, Ellis G Levine, Pawel Kalinski

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007381; DOI: 10.1136/jitc-2023-007381
Tumor cell-induced macrophage senescence plays a pivotal role in tumor initiation followed by stable growth in immunocompetent condition
Haruka Wada, Ryo Otsuka, Wilfred T V Germeraad, Tomoki Murata, Toru Kondo, Ken-ichiro Seino

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e006677; DOI: 10.1136/jitc-2023-006677
Timed adoptive T cell transfer during chemotherapy in patients with recurrent platinum-sensitive epithelial ovarian cancer
Els M E Verdegaal, Saskia J Santegoets, Marij J P Welters, Linda de Bruin, Marten Visser, Caroline E van der Minne, Pita M de Kok, Nikki M Loof, Sanne Boekestijn, Inge Roozen, Inge M Westra, Pauline Meij, Sjoerd H Van der Burg, Judith R Kroep

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007697; DOI: 10.1136/jitc-2023-007697
New perspectives in cancer immunotherapy: targeting IL-6 cytokine family
Maria Florencia Soler, Andrea Abaurrea, Peio Azcoaga, Angela M Araujo, Maria M Caffarel

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007530; DOI: 10.1136/jitc-2023-007530
Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer
Kelly Boelaars, Laura Goossens-Kruijssen, Di Wang, Charlotte M de Winde, Ernesto Rodriguez, Dimitri Lindijer, Babet Springer, Irene van der Haar Àvila, Aram de Haas, Laetitia Wehry, Louis Boon, Reina E Mebius, Nadine van Montfoort, Manfred Wuhrer, Joke M M den Haan, Sandra J van Vliet, Yvette van Kooyk

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007805; DOI: 10.1136/jitc-2023-007805
MDR1-expressing CD4⁺ T cells with Th1.17 features resist to neoadjuvant chemotherapy and are associated with breast cancer clinical response
Anthony Di Roio, Margaux Hubert, Laurie Besson, Marion Bossennec, Céline Rodriguez, Yenkel Grinberg-Bleyer, Guilhem Lalle, Lyvia Moudombi, Raphael Schneider, Cyril Degletagne, Isabelle Treilleux, Daniel J Campbell, Séverine Metzger, Thomas Duhen, Olivier Trédan, Christophe Caux, Christine Ménétrier-Caux

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007733; DOI: 10.1136/jitc-2023-007733
Loss of ADAR1 in macrophages in combination with interferon gamma suppresses tumor growth by remodeling the tumor microenvironment
Weiwei Lin, Yikai Luo, Jie Wu, Haowan Zhang, Ge Jin, Chahua Guo, Hang Zhou, Han Liang, Xiaoyan Xu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007402; DOI: 10.1136/jitc-2023-007402

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