Tumor Microenvironment

Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor
Dan You, Stephen Hillerman, Gregory Locke, Charu Chaudhry, Caitlyn Stromko, Anwar Murtaza, Yi Fan, Jennifer Koenitzer, Yali Chen, Stephanie Briceno, Rajarshi Bhadra, Elizabeth Duperret, Johnni Gullo-Brown, Chan Gao, Dandan Zhao, John Feder, Joshua Curtin, Andrew P Degnan, Godwin Kumi, Mark Wittman, Benjamin M Johnson, Karen E Parrish, Giridharan Gokulrangan, John Morrison, Michael Quigley, John T Hunt, Luisa Salter-Cid, Emma Lees, Miguel A Sanjuan, Jinqi Liu

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001402; DOI: 10.1136/jitc-2020-001402
Therapy of lymphoma by immune checkpoint inhibitors: the role of T cells, NK cells and cytokine-induced tumor senescence
Fatima Ahmetlic, Josia Fauser, Tanja Riedel, Vera Bauer, Carolin Flessner, Nadine Hömberg, Roman Hennel, Ellen Brenner, Kirsten Lauber, Martin Röcken, Ralph Mocikat

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001660; DOI: 10.1136/jitc-2020-001660
CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
Moran Yang, Jiaqi Lu, Guodong Zhang, Yiying Wang, Mengdi He, Qing Xu, Congjian Xu, Haiou Liu

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001136; DOI: 10.1136/jitc-2020-001136
Neuroblastoma: an ongoing cold front for cancer immunotherapy
Paul T Kennedy, Demetra Zannoupa, Meong Hi Son, Lekh N Dahal, John F Woolley

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007798; DOI: 10.1136/jitc-2023-007798
Systemic infusion of TLR3-ligand and IFN-α in patients with breast cancer reprograms local tumor microenvironments for selective CTL influx
Shipra Gandhi, Mateusz Opyrchal, Melissa J Grimm, Ronald T Slomba, Kathleen M Kokolus, Agnieszka Witkiewicz, Kristopher Attwood, Adrienne Groman, Lauren Williams, Mary Lynne Tarquini, Paul K Wallace, Kah Teong Soh, Hans Minderman, Orla Maguire, Tracey L O’Connor, Amy P Early, Ellis G Levine, Pawel Kalinski

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007381; DOI: 10.1136/jitc-2023-007381
Tumor cell-induced macrophage senescence plays a pivotal role in tumor initiation followed by stable growth in immunocompetent condition
Haruka Wada, Ryo Otsuka, Wilfred T V Germeraad, Tomoki Murata, Toru Kondo, Ken-ichiro Seino

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e006677; DOI: 10.1136/jitc-2023-006677
Timed adoptive T cell transfer during chemotherapy in patients with recurrent platinum-sensitive epithelial ovarian cancer
Els M E Verdegaal, Saskia J Santegoets, Marij J P Welters, Linda de Bruin, Marten Visser, Caroline E van der Minne, Pita M de Kok, Nikki M Loof, Sanne Boekestijn, Inge Roozen, Inge M Westra, Pauline Meij, Sjoerd H Van der Burg, Judith R Kroep

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007697; DOI: 10.1136/jitc-2023-007697
New perspectives in cancer immunotherapy: targeting IL-6 cytokine family
Maria Florencia Soler, Andrea Abaurrea, Peio Azcoaga, Angela M Araujo, Maria M Caffarel

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007530; DOI: 10.1136/jitc-2023-007530
MDR1-expressing CD4⁺ T cells with Th1.17 features resist to neoadjuvant chemotherapy and are associated with breast cancer clinical response
Anthony Di Roio, Margaux Hubert, Laurie Besson, Marion Bossennec, Céline Rodriguez, Yenkel Grinberg-Bleyer, Guilhem Lalle, Lyvia Moudombi, Raphael Schneider, Cyril Degletagne, Isabelle Treilleux, Daniel J Campbell, Séverine Metzger, Thomas Duhen, Olivier Trédan, Christophe Caux, Christine Ménétrier-Caux

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007733; DOI: 10.1136/jitc-2023-007733
Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer
Kelly Boelaars, Laura Goossens-Kruijssen, Di Wang, Charlotte M de Winde, Ernesto Rodriguez, Dimitri Lindijer, Babet Springer, Irene van der Haar Àvila, Aram de Haas, Laetitia Wehry, Louis Boon, Reina E Mebius, Nadine van Montfoort, Manfred Wuhrer, Joke M M den Haan, Sandra J van Vliet, Yvette van Kooyk

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007805; DOI: 10.1136/jitc-2023-007805

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