Tumor Microenvironment

Targeting myeloid checkpoint Siglec-10 reactivates antitumor immunity and improves anti-programmed cell death 1 efficacy in gastric cancer
Kunpeng Lv, Mengyao Sun, Hanji Fang, Jieti Wang, Chao Lin, Hao Liu, Heng Zhang, He Li, Hongyong He, Yun Gu, Ruochen Li, Fei Shao, Jiejie Xu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007669; DOI: 10.1136/jitc-2023-007669
Comprehensive analyses of immune tumor microenvironment in papillary renal cell carcinoma
Manon de Vries-Brilland, Nathalie Rioux-Leclercq, Maxime Meylan, Jonathan Dauvé, Christophe Passot, Elena Spirina-Menand, Ronan Flippot, Gaëlle Fromont, Gwenaelle Gravis, Lionnel Geoffrois, Christine Chevreau, Fréderic Rolland, Ellen Blanc, Félix Lefort, Alain Ravaud, Marine Gross-Goupil, Bernard Escudier, Sylvie Negrier, Laurence Albiges

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e006885; DOI: 10.1136/jitc-2023-006885
Loss of ADAR1 in macrophages in combination with interferon gamma suppresses tumor growth by remodeling the tumor microenvironment
Weiwei Lin, Yikai Luo, Jie Wu, Haowan Zhang, Ge Jin, Chahua Guo, Hang Zhou, Han Liang, Xiaoyan Xu

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e007402; DOI: 10.1136/jitc-2023-007402
Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, Jose Gonzalez-Gomariz, Celia Gomar, Joan Salvador Russo-Cabrera, Irene Olivera, Assunta Cirella, Myriam Fernandez-Sendin, Maite Alvarez, Alvaro Teijeira, Cigdem Atay, José Medina-Echeverz, Maria Hinterberger, Hubertus Hochrein, Ignacio Melero, Pedro Berraondo, Fernando Aranda

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e006702; DOI: 10.1136/jitc-2023-006702
Patient-derived lymphoma spheroids integrating immune tumor microenvironment as preclinical follicular lymphoma models for personalized medicine
Carla Faria, Fabien Gava, Pauline Gravelle, Juan Garcia Valero, Celia Dobaño-López, Nathalie Van Acker, Cathy Quelen, Gael Jalowicki, Renaud Morin, Cédric Rossi, Jean-Michel Lagarde, Jean-Jacques Fournié, Loïc Ysebaert, Camille Laurent, Patricia Pérez-Galán, Christine Bezombes

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007156; DOI: 10.1136/jitc-2023-007156
Multiplex imaging in immuno-oncology
Chen Zhao, Ronald N Germain

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e006923; DOI: 10.1136/jitc-2023-006923
MCT4 blockade increases the efficacy of immune checkpoint blockade
Nathalie Babl, Sonja-Maria Decking, Florian Voll, Michael Althammer, Ada Sala-Hojman, Roberta Ferretti, Clarissa Korf, Christian Schmidl, Lisa Schmidleithner, Benedikt Nerb, Carina Matos, Gudrun E Koehl, Peter Siska, Christina Bruss, Fabian Kellermeier, Katja Dettmer, Peter J Oefner, Marvin Wichland, Ines Ugele, Christopher Bohr, Wolfgang Herr, Shivapriya Ramaswamy, Timo Heinrich, Christian Herhaus, Marina Kreutz, Kathrin Renner

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007349; DOI: 10.1136/jitc-2023-007349
Classification of the tumor immune microenvironment and associations with outcomes in patients with metastatic melanoma treated with immunotherapies
Nurudeen A Adegoke, Tuba N Gide, Yizhe Mao, Camelia Quek, Ellis Patrick, Matteo S Carlino, Serigne N Lo, Alexander Maxwell Menzies, Ines Pires da Silva, Ismael A Vergara, Georgina Long, Richard A Scolyer, James S Wilmott

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007144; DOI: 10.1136/jitc-2023-007144
Identification of tumor-intrinsic drivers of immune exclusion in acral melanoma
Ryan C Augustin, Sarah Newman, Aofei Li, Marion Joy, Maureen Lyons, Mary P Pham, Peter Lucas, Katelyn Smith, Cindy Sander, Brian Isett, Diwakar Davar, Yana G Najjar, Hassane M Zarour, John M Kirkwood, Jason John Luke, Riyue Bao

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007567; DOI: 10.1136/jitc-2023-007567
Divergent tumor and immune cell reprogramming underlying immunotherapy response and immune-related adverse events in lung squamous cell carcinoma
Minjiang Chen, Pengfei Ma, Yongchang Zhang, Dong Wang, Zhuang Yu, Yujie Fu, Xiaojing Zhao, Mengzhao Wang, Guanglei Zhuang, Ying Jing

Journal for ImmunoTherapy of Cancer Oct 2023, 11 (10) e007305; DOI: 10.1136/jitc-2023-007305

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