Tumor Microenvironment

Dissecting tumor lymphocyte infiltration to predict benefit from immune-checkpoint inhibitors in metastatic colorectal cancer: lessons from the AtezoT RIBE study
Roberto Moretto, Daniele Rossini, Aurélie Catteau, Carlotta Antoniotti, Mirella Giordano, Alessandra Boccaccino, Clara Ugolini, Agnese Proietti, Veronica Conca, Alboukadel Kassambara, Filippo Pietrantonio, Lisa Salvatore, Sara Lonardi, Stefano Tamberi, Emiliano Tamburini, Anello Marcello Poma, Jacques Fieschi, Gabriella Fontanini, Gianluca Masi, Jérôme Galon, Chiara Cremolini

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006633; DOI: 10.1136/jitc-2022-006633
Tumor and immune remodeling following radiotherapy in human renal cell carcinoma
Jacky Chow, Adil Khan, Madeline Gaudieri, Brianna J Wasik, Alexis Conway, Kah Teong Soh, Elizabeth A Repasky, Thomas Schwaab, Paul K Wallace, Scott I Abrams, Anurag K Singh, Jason B Muhitch

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006392; DOI: 10.1136/jitc-2022-006392
Barriers to immune cell infiltration in tumors
Marit M Melssen, Natasha D Sheybani, Katie M Leick, Craig L Slingluff

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006401; DOI: 10.1136/jitc-2022-006401
Intratumoral tertiary lymphoid structure (TLS) maturation is influenced by draining lymph nodes of lung cancer
Miao He, Qihua He, Xiuyu Cai, Jun Liu, Hongshen Deng, Feng Li, Ran Zhong, Yi Lu, Haoxin Peng, Xiangrong Wu, Zisheng Chen, Shen Lao, Caichen Li, Jianfu Li, Jianxing He, Wenhua Liang

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e005539; DOI: 10.1136/jitc-2022-005539
Irreversible electroporation augments β-glucan induced trained innate immunity for the treatment of pancreatic ductal adenocarcinoma
Matthew R Woeste, Rejeena Shrestha, Anne E Geller, Shu Li, Diego Montoya-Durango, Chuanlin Ding, Xiaoling Hu, Hong Li, Aaron Puckett, Robert A Mitchell, Traci Hayat, Min Tan, Yan Li, Kelly M McMasters, Robert C G Martin, Jun Yan

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006221; DOI: 10.1136/jitc-2022-006221
Cancer cell genotype associated tumor immune microenvironment exhibits differential response to therapeutic STING pathway activation in high-grade serous ovarian cancer
Noor Shakfa, Deyang Li, Gwenaelle Conseil, Elizabeth D Lightbody, Juliette Wilson-Sanchez, Ali Hamade, Stephen Chenard, Natasha A. Jawa, Brian J. Laight, Afrakoma Afriyie-Asante, Kathrin Tyryshkin, Martin Koebel, Madhuri Koti

Journal for ImmunoTherapy of Cancer Apr 2023, 11 (4) e006170; DOI: 10.1136/jitc-2022-006170
Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment
Christine McInnis, Shilpa Bhatia, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Ann Marie Egloff, Lakshmi Srinivasan, Daniel C Pregibon, Anthony J Coyle, Glenn J Hanna

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e006721; DOI: 10.1136/jitc-2023-006721
Targeting tumor vasculature to improve antitumor activity of T cells armed ex vivo with T cell engaging bispecific antibody
Jeong A Park, Madelyn Espinosa-Cotton, Hong-fen Guo, Sebastien Monette, Nai-Kong V Cheung

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e006680; DOI: 10.1136/jitc-2023-006680
Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy
Rasmus Erik Johansson Mortensen, Morten Orebo Holmström, Thomas Landkildehus Lisle, Jane P Hasselby, Gro L Willemoe, Özcan Met, Inge Marie Svane, Julia Johansen, Dorte L Nielsen, Inna M Chen, Mads Hald Andersen

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e006432; DOI: 10.1136/jitc-2022-006432
Immune and pathologic responses in patients with localized prostate cancer who received daratumumab (anti-CD38) or edicotinib (CSF-1R inhibitor)
Bilal A Siddiqui, Brian F Chapin, Sonali Jindal, Fei Duan, Sreyashi Basu, Shalini S Yadav, Ai-Di Gu, Alexsandra B Espejo, Michelle Kinder, Curtis A Pettaway, John F Ward, Rebecca S S Tidwell, Patricia Troncoso, Paul G Corn, Christopher J Logothetis, Roland Knoblauch, Natalie Hutnick, Marco Gottardis, Charles G Drake, Padmanee Sharma, Sumit K Subudhi

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e006262; DOI: 10.1136/jitc-2022-006262

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