Tumor

PD-L1 quantification across tumor types using the reverse phase protein microarray: implications for precision medicine
Elisa Baldelli, K Alex Hodge, Guido Bellezza, Neil J Shah, Guido Gambara, Angelo Sidoni, Martina Mandarano, Chamodya Ruhunusiri, Bryant Dunetz, Maysa Abu-Khalaf, Julia Wulfkuhle, Rosa I Gallagher, Lance Liotta, Johann de Bono, Niven Mehra, Ruth Riisnaes, Antonella Ravaggi, Franco Odicino, Maria Isabella Sereni, Matthew Blackburn, Angela Zupa, Giuseppina Improta, Perry Demsko, Lucio Crino', Vienna Ludovini, Giuseppe Giaccone, Emanuel F Petricoin, Mariaelena Pierobon

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002179; DOI: 10.1136/jitc-2020-002179
MET overexpression contributes to STAT4-PD-L1 signaling activation associated with tumor-associated, macrophages-mediated immunosuppression in primary glioblastomas
Qiang-Wei Wang, Li-Hua Sun, Ying Zhang, Zheng Wang, Zheng Zhao, Zhi-Liang Wang, Kuan-Yu Wang, Guan-Zhang Li, Jian-Bao Xu, Chang-Yuan Ren, Wen-Ping Ma, Hong-Jun Wang, Shou-Wei Li, Yong-Jian Zhu, Tao Jiang, Zhao-Shi Bao

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002451; DOI: 10.1136/jitc-2021-002451
Spatially resolved analysis of the T cell immune contexture in lung cancer-associated brain metastases
Benjamin Y Lu, Richa Gupta, Adam Aguirre-Ducler, Nicole Gianino, Hailey Wyatt, Matthew Ribeiro, Veronica L Chiang, Joseph N Contessa, Adebowale J Adeniran, Lucia B Jilaveanu, Harriet M Kluger, Kurt A Schalper, Sarah B Goldberg

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002684; DOI: 10.1136/jitc-2021-002684
Real-world performance of blood-based proteomic profiling in first-line immunotherapy treatment in advanced stage non-small cell lung cancer
Patricia Rich, R Brian Mitchell, Eric Schaefer, Paul R Walker, John W Dubay, Jason Boyd, David Oubre, Ray Page, Mazen Khalil, Suman Sinha, Scott Boniol, Hafez Halawani, Edgardo S Santos, Warren Brenner, James M Orsini, Emily Pauli, Jonathan Goldberg, Andrea Veatch, Mitchell Haut, Bassam Ghabach, Savita Bidyasar, Maria Quejada, Waseemullah Khan, Kan Huang, Linda Traylor, Wallace Akerley

Journal for ImmunoTherapy of Cancer Oct 2021, 9 (10) e002989; DOI: 10.1136/jitc-2021-002989
Pan-cancer landscape of CD274 (PD-L1) rearrangements in 283,050 patient samples, its correlation with PD-L1 protein expression, and immunotherapy response
Andrew D Kelly, Karthikeyan Murugesan, Zheng Kuang, Meagan Montesion, Jeffrey S Ross, Lee A Albacker, Richard S P Huang, Douglas I Lin, Umut Demirci, James Creeden

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003550; DOI: 10.1136/jitc-2021-003550
Genomic alterations in biliary tract cancer predict prognosis and immunotherapy outcomes
Xiaofeng Chen, Deqiang Wang, Jing Liu, Jingrong Qiu, Jun Zhou, Jieer Ying, Yan Shi, Zhaoxia Wang, Haizhou Lou, Jiuwei Cui, Jingdong Zhang, Yunpeng Liu, Fengjiao Zhao, Lanlan Pan, Jianyi Zhao, Dongqin Zhu, Shiqing Chen, Xiangcheng Li, Xue Li, Liuqing Zhu, Yang Shao, Yongqian Shu

Journal for ImmunoTherapy of Cancer Nov 2021, 9 (11) e003214; DOI: 10.1136/jitc-2021-003214
Short-term response to immune-chemotherapy and immune features of a ceritinib-resistant patient with ROS1-rearranged lung adenocarcinoma
Dongsheng Yue, Juanjuan Qian, Zhipeng Chen, Bin Zhang, Peng Chen, Lei Zhang, Jingjing Li, Henghui Zhang, Changli Wang

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001967; DOI: 10.1136/jitc-2020-001967
Adrenal gland as a sanctuary site for immunotherapy in patients with microsatellite instability-high metastatic colorectal cancer
Romain Cohen, Vincent Jonchère, Christelle De La Fouchardière, Toky Ratovomanana, Quentin Letourneur, Mira Ayadi, Lucile Armenoult, Adrien Buisson, Matthieu Sarabi, Anna Pellat, Raphael Colle, Francois Paye, Pierre Meeus, Magali Svrcek, Alex Duval, Thierry Andre

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001903; DOI: 10.1136/jitc-2020-001903
CMTM6 and PD-L1 coexpression is associated with an active immune microenvironment and a favorable prognosis in colorectal cancer
Qi-Hua Peng, Chun-Hua Wang, Hong-Min Chen, Rong-Xin Zhang, Zhi-Zhong Pan, Zhen-Hai Lu, Gao-Yuan Wang, Xin Yue, Wenlin Huang, Ran-Yi Liu

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001638; DOI: 10.1136/jitc-2020-001638
Therapeutic depletion of CCR8⁺ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
Helena Van Damme, Bruno Dombrecht, Máté Kiss, Heleen Roose, Elizabeth Allen, Eva Van Overmeire, Daliya Kancheva, Liesbet Martens, Aleksandar Murgaski, Pauline Madeleine Rachel Bardet, Gillian Blancke, Maude Jans, Evangelia Bolli, Maria Solange Martins, Yvon Elkrim, James Dooley, Louis Boon, Julia Katharina Schwarze, Frank Tacke, Kiavash Movahedi, Niels Vandamme, Bart Neyns, Sebahat Ocak, Isabelle Scheyltjens, Lars Vereecke, Frank Aboubakar Nana, Pascal Merchiers, Damya Laoui, Jo Agnes Van Ginderachter

Journal for ImmunoTherapy of Cancer Feb 2021, 9 (2) e001749; DOI: 10.1136/jitc-2020-001749

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