Vaccination

Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C
Celia Gomar, Claudia Augusta Di Trani, Angela Bella, Leire Arrizabalaga, Jose Gonzalez-Gomariz, Myriam Fernandez-Sendin, Maite Alvarez, Joan Salvador Russo-Cabrera, Nuria Ardaiz, Fernando Aranda, Timo Schippers, Marisol Quintero, Ignacio Melero, Klaus K Orlinger, Henning Lauterbach, Pedro Berraondo

Journal for ImmunoTherapy of Cancer Apr 2024, 12 (4) e008287; DOI: 10.1136/jitc-2023-008287
Novel peptide-based oncolytic vaccine for enhancement of adaptive antitumor immune response via co-engagement of innate Fcγ and Fcα receptors
Sara Feola, Firas Hamdan, Salvatore Russo, Jacopo Chiaro, Manlio Fusciello, Michaela Feodoroff, Gabriella Antignani, Federica D'Alessio, Riikka Mölsä, Virpi Stigzelius, Paolo Bottega, Sari Pesonen, Jeanette Leusen, Mikaela Grönholm, Vincenzo Cerullo

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008342; DOI: 10.1136/jitc-2023-008342
Pattern recognition receptor agonists in pathogen vaccines mediate antitumor T-cell cross-priming
Mark Aleynick, Judit Svensson-Arvelund, Gvantsa Pantsulaia, Kristy Kim, Samuel A Rose, Ranjan Upadhyay, Michael Yellin, Henry Marsh, Daniel Oreper, Suchit Jhunjhunwala, Christine Carine Moussion, Miriam Merad, Brian D Brown, Joshua D Brody

Journal for ImmunoTherapy of Cancer Jul 2023, 11 (7) e007198; DOI: 10.1136/jitc-2023-007198
Phase 2 trial of a DNA vaccine (pTVG-HP) and nivolumab in patients with castration-sensitive non-metastatic (M0) prostate cancer
Douglas G McNeel, Hamid Emamekhoo, Jens C Eickhoff, Christos E Kyriakopoulos, Ellen Wargowski, Tommaso P Tonelli, Laura E Johnson, Glenn Liu

Journal for ImmunoTherapy of Cancer Dec 2023, 11 (12) e008067; DOI: 10.1136/jitc-2023-008067
Trojan-horse silk fibroin nanocarriers loaded with a re-call antigen to redirect immunity against cancer
Elia Bari, Francesca Ferrera, Tiziana Altosole, Sara Perteghella, Pierluigi Mauri, Rossana Rossi, Giulia Passignani, Luca Mastracci, Martina Galati, Giuseppina Iliana Astone, Maddalena Mastrogiacomo, Patrizio Castagnola, Daniela Fenoglio, Dario Di Silvestre, Maria Luisa Torre, Gilberto Filaci

Journal for ImmunoTherapy of Cancer Jan 2023, 11 (1) e005916; DOI: 10.1136/jitc-2022-005916
Intradermal vaccination of HPV-16 E6 synthetic peptides conjugated to an optimized Toll-like receptor 2 ligand shows safety and potent T cell immunogenicity in patients with HPV-16 positive (pre-)malignant lesions
Frank M Speetjens, Marij J P Welters, Marije Slingerland, Mariette I E van Poelgeest, Peggy J de Vos van Steenwijk, Inge Roozen, Sanne Boekestijn, Nikki M Loof, Gijs G Zom, A Rob P M Valentijn, Willem-Jan Krebber, Nico J Meeuwenoord, Catharina A H Janssen, Cornelis J M Melief, Gijs A van der Marel, Dmitri V Filippov, Sjoerd H van der Burg, Hans Gelderblom, Ferry Ossendorp

Journal for ImmunoTherapy of Cancer Oct 2022, 10 (10) e005016; DOI: 10.1136/jitc-2022-005016
Arginase-2-specific cytotoxic T cells specifically recognize functional regulatory T cells
Stine Emilie Weis-Banke, Thomas Landkildehus Lisle, Maria Perez-Penco, Aimilia Schina, Mie Linder Hübbe, Majken Siersbæk, Morten Orebo Holmström, Mia Aaboe Jørgensen, Inge Marie Svane, Özcan Met, Niels Ødum, Daniel Hargbøl Madsen, Marco Donia, Lars Grøntved, Mads Hald Andersen

Journal for ImmunoTherapy of Cancer Oct 2022, 10 (10) e005326; DOI: 10.1136/jitc-2022-005326
CCL21-DC in situ vaccination in murine NSCLC overcomes resistance to immunotherapy and generates systemic tumor-specific immunity
Ramin Salehi-Rad, Raymond J Lim, Yushen Du, Linh M Tran, Rui Li, Stephanie L Ong, Zi Ling Huang, Camelia Dumitras, Tianhao Zhang, Stacy J Park, William Crosson, Bitta Kahangi, Jensen Abascal, Christopher Seet, Michael Oh, Maryam Shabihkhani, Manash Paul, Kostyantyn Krysan, Aaron E Lisberg, Edward B Garon, Bin Liu, Steven M Dubinett

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006896; DOI: 10.1136/jitc-2023-006896
Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity
Xiaofei Yu, Wenjie Liu, Shixian Chen, Xueqian Cheng, Patrick A Paez, Tuanwei Sun, Fang Yuan, Chunyan Wei, Joseph W Landry, Andrew S Poklepovic, Harry D Bear, John R Subjeck, Elizabeth Repasky, Chunqing Guo, Xiang-Yang Wang

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001595; DOI: 10.1136/jitc-2020-001595
Skin immunization for effective treatment of multifocal melanoma refractory to PD1 blockade and Braf inhibitors
Xingxing Hao, Louis D Falo III, Guo Chen, Jiying Zhang, Cara D Carey, Walter J Storkus, Louis D Falo Jr, Zhaoyang You

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001179; DOI: 10.1136/jitc-2020-001179

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