Vaccination

Use of plasma ctDNA as a potential biomarker for longitudinal monitoring of a patient with metastatic high-risk upper tract urothelial carcinoma receiving pembrolizumab and personalized neoepitope-derived multipeptide vaccinations: a case report
Carolin Blumendeller, Julius Boehme, Maximilian Frick, Martin Schulze, Antje Rinckleb, Christina Kyzirakos, Simone Kayser, Maria Kopp, Sabine Kelkenberg, Natalia Pieper, Oliver Bartsch, Dirk Hadaschick, Florian Battke, Arnulf Stenzl, Saskia Biskup

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001406; DOI: 10.1136/jitc-2020-001406
Intraperitoneal administration of a modified vaccinia virus Ankara confers single-chain interleukin-12 expression to the omentum and achieves immune-mediated efficacy against peritoneal carcinomatosis
Ángela Bella, Leire Arrizabalaga, Claudia Augusta Di Trani, Jose Gonzalez-Gomariz, Celia Gomar, Joan Salvador Russo-Cabrera, Irene Olivera, Assunta Cirella, Myriam Fernandez-Sendin, Maite Alvarez, Alvaro Teijeira, Cigdem Atay, José Medina-Echeverz, Maria Hinterberger, Hubertus Hochrein, Ignacio Melero, Pedro Berraondo, Fernando Aranda

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (11) e006702; DOI: 10.1136/jitc-2023-006702
Heterologous prime-boost vaccination targeting MAGE-type antigens promotes tumor T-cell infiltration and improves checkpoint blockade therapy
James McAuliffe, Hok Fung Chan, Laurine Noblecourt, Ramiro Andrei Ramirez-Valdez, Vinnycius Pereira-Almeida, Yaxuan Zhou, Emily Pollock, Federica Cappuccini, Irina Redchenko, Adrian VS Hill, Carol Sze Ki Leung, Benoit J Van den Eynde

Journal for ImmunoTherapy of Cancer Sep 2021, 9 (9) e003218; DOI: 10.1136/jitc-2021-003218
First-in-human, phase 1 study of PF-06753512, a vaccine-based immunotherapy regimen (VBIR), in non-metastatic hormone-sensitive biochemical recurrence and metastatic castration-resistant prostate cancer (mCRPC)
Karen A Autio, Celestia S Higano, Luke Nordquist, Leonard J Appleman, Tian Zhang, Xin-Hua Zhu, Hani Babiker, Nicholas J Vogelzang, Sandip M Prasad, Michael T Schweizer, Ravi A Madan, Stephane Billotte, Nora Cavazos, Orlaith Bogg, Ray Li, Kam Chan, Helen Cho, Megan Kaneda, I-Ming Wang, Jenny Zheng, Szu-Yu Tang, Robert Hollingsworth, Kenneth A Kern, Daniel P Petrylak

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e005702; DOI: 10.1136/jitc-2022-005702
Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy
Rasmus Erik Johansson Mortensen, Morten Orebo Holmström, Thomas Landkildehus Lisle, Jane P Hasselby, Gro L Willemoe, Özcan Met, Inge Marie Svane, Julia Johansen, Dorte L Nielsen, Inna M Chen, Mads Hald Andersen

Journal for ImmunoTherapy of Cancer Mar 2023, 11 (3) e006432; DOI: 10.1136/jitc-2022-006432
T cell responses against SARS-CoV-2 and its Omicron variant in a patient with B cell lymphoma after multiple doses of a COVID-19 mRNA vaccine
Djordje Atanackovic, Robert J Kreitman, Jeffrey Cohen, Nancy M Hardy, Destiny Omili, Thierry Iraguha, Peter D Burbelo, Etse Gebru, Xiaoxuan Fan, John Baddley, Tim Luetkens, Saurabh Dahiya, Aaron P Rapoport

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004953; DOI: 10.1136/jitc-2022-004953
Preinduced reovirus-specific T-cell immunity enhances the anticancer efficacy of reovirus therapy
Christianne Groeneveldt, Priscilla Kinderman, Jordi J C van Stigt Thans, Camilla Labrie, Lisa Griffioen, Marjolein Sluijter, Diana J M van den Wollenberg, Rob C Hoeben, Joke M M den Haan, Sjoerd H van der Burg, Thorbald van Hall, Nadine van Montfoort

Journal for ImmunoTherapy of Cancer Jul 2022, 10 (7) e004464; DOI: 10.1136/jitc-2021-004464
Immune checkpoint silencing using RNAi-incorporated nanoparticles enhances antitumor immunity and therapeutic efficacy compared with antibody-based approaches
Ji Eun Won, Youngseon Byeon, Tae In Wi, Chan Mi Lee, Ju Hyeong Lee, Tae Heung Kang, Jeong-Won Lee, YoungJoo Lee, Yeong-Min Park, Hee Dong Han

Journal for ImmunoTherapy of Cancer Feb 2022, 10 (2) e003928; DOI: 10.1136/jitc-2021-003928
Bedside formulation of a personalized multi-neoantigen vaccine against mammary carcinoma
Mona O Mohsen, Daniel E Speiser, Justine Michaux, HuiSong Pak, Brian J Stevenson, Monique Vogel, Varghese Philipose Inchakalody, Simone de Brot, Said Dermime, Georges Coukos, Michal Bassani-Sternberg, Martin F Bachmann

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e002927; DOI: 10.1136/jitc-2021-002927
Large-scale manufacturing and characterization of CMV-CD19CAR T cells
Xiuli Wang, Ryan Urak, Miriam Walter, Min Guan, Tianxu Han, Vibhuti Vyas, Sheng-Hsuan Chien, Brenna Gittins, Mary C Clark, Sally Mokhtari, Angelo Cardoso, Don J Diamond, John Zaia, Stephen J Forman, Ryotaro Nakamura

Journal for ImmunoTherapy of Cancer Jan 2022, 10 (1) e003461; DOI: 10.1136/jitc-2021-003461

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