Regular ArticleCharacterization of recombinant soluble human transforming growth factor-β receptor Type II (rhTGF-βsRII)
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In vivo induction of regulatory T cells promotes allergen tolerance and suppresses allergic contact dermatitis
2017, Journal of Controlled ReleaseHSP70 increases extracellular matrix production by human vascular smooth muscle through TGF-β1 up-regulation
2013, International Journal of Biochemistry and Cell BiologyCitation Excerpt :ERK and JNK are the kinases responsible of c-Fos and c-Jun phosphorylation, respectively (Gille et al., 1992). Both phosphorylated proteins form the transcriptional factor AP-1 that regulates TGF-β1 by binding to specific sites as we and others have shown (Tsang et al., 1995; Iglesias-De La Cruz et al., 2001; Ortega-Velazquez et al., 2004; Rhyu et al., 2005; Ruiz-Torres et al., 2007; Saura et al., 2005; González-Ramos et al., 2012). TLR4 downstream signalling depends on different molecules such as myeloid differentiation primary-response protein-88 (MyD88) or TIR domain-containing adaptor protein (TRIF) (Kawai and Akira, 2010) that ultimately lead to the activation of MAPKs (Newton and Dixit, 2012).
Stromal fibroblast-bone marrow-derived cell interactions: Implications for myofibroblast development in the cornea
2012, Experimental Eye Research
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