Cell
Isolation of deletion and substitution mutants of adenovirus type 5
References (24)
- et al.
- et al.
Virology
(1977) - et al.
Cell
(1976) - et al.
J. Mol. Biol.
(1973) - et al.
J. Biol. Chem.
(1970) - et al.
J. Mol. Biol.
(1977) - et al.
J. Mol. Biol.
(1972) - et al.
J. Mol. Biol.
(1975) - et al.
J. Mol. Biol.
(1974) - et al.
Virology
(1976)
J. Mol. Biol.
Virology
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Effect of adenovirus infection on transgene expression under the adenoviral MLP/TPL and the CMVie promoter/enhancer in CHO cells
2017, Journal of Genetic Engineering and BiotechnologyCitation Excerpt :In this study, we tested whether providing additional adenovirus sequences, in trans, could enhance MLP-TPL activity to that observed for CMVie, using a GFP reporter gene and assaying for transcript and protein levels. For this purpose we made use of the adenovirus dl309, which has the same properties as the wild-type adenovirus serotype 5 with the exception of the E3 region [4,20,21]. CHO cells were chosen as the cellular background for this study because they are the most widely used mammalian cell line for recombinant protein production [43].
Quantitative proteomic discovery of dynamic epigenome changes that control human cytomegalovirus (HCMV) infection
2014, Molecular and Cellular ProteomicsProspects for oral replicating adenovirus-vectored vaccines
2013, VaccineCitation Excerpt :Most current rAd vaccine candidates are transgene expression vectors, commonly engineered to express a foreign gene inserted into early region 1 (E1) or, occasionally, early region 4 (E4) of the genome [14]. E1 and E4 are essential for viral replication, and most such rAds are replication-defective [15–17]. Extensive experience with defective recombinants in humans and animal models has shown promise in several cases [18].
AdHTS: A high-throughput system for generating recombinant adenoviruses
2012, Journal of BiotechnologyCitation Excerpt :But their use in functional genomics studies has been limited due to the difficulties in constructing recombinant Ades. The large genome size and very low infectivity of naked Ad DNA with less than 30 plaque-forming units (pfu) per μg DNA has become major obstacle for high-throughput production of recombinant Ades (Jones and Shenk, 1978; Sharp et al., 1976). Ad has a double-stranded linear DNA genome with Terminal protein (TP) covalently linked to the 5′ ends of its genome (Pronk et al., 1992).
Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal
2006, Free Radical Biology and Medicine