Surgical stress induces a shift in the type-1/type-2 T-helper cell balance, suggesting down-regulation of cell-mediated and up-regulation of antibody-mediated immunity commensurate to the trauma*
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2023, British Journal of AnaesthesiaThe immune response to major gastrointestinal cancer surgery and potential implications for adjuvant immunotherapy
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2020, Computers in Biology and MedicineUreaplasma parvum ventriculitis related to surgery and ventricular peritoneal drainage
2020, Journal of Infection and ChemotherapyCitation Excerpt :Ureaplasma is known to cause local infection after genitourinary surgery [13–15]; extragenital invasive infections mostly occur in severely immunocompromised patients [2–6]. However a few invasive extragenital infections with Ureaplasma have been described postoperatively at the site of surgery in previously immunocompetent patient probably linked to surgery-related immune impairment (impaired cell mediated immunity, breakage of skin and mucosal barrier, release of cortisol and catecholamines,... [16,17]); five cases occurred in patients following cardiovascular procedures [18–22] and very recently, a case of central nervous system infection after neurosurgical procedure has been described [23]. After exclusion of underlying immune deficiency we believe that surgery-related immune impairment may also be the cause of invasive Ureaplasma infection in our patient.
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Supported by a grant from the DFG (Deutsche Forschungsgemeinschaft)