Cancer Cell
Volume 22, Issue 4, 16 October 2012, Pages 494-505
ArticleElevated Epidermal Thymic Stromal Lymphopoietin Levels Establish an Antitumor Environment in the Skin
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Graphical Abstract
Highlights
► RBPj-deficient skin with severe Th2 inflammation is resistant to tumorigenesis ► TSLP signaling is responsible for tumor resistance in Notch-signaling deficient skin ► TSLP acts through CD4+ T cells to establish tumor resistance ► Induction of TSLP in wild-type skin can produce resistance to tumorigenesis
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