Immunity
Volume 37, Issue 6, 14 December 2012, Pages 1130-1144
ResourceNetwork Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
Under an Elsevier user license
open archive
Highlights
► Network analysis reveals pathways and hub genes in memory versus exhausted CD8 T cells ► Memory and exhausted CD8 T cells have partially nonoverlapping modules and hubs ► Distinct modules include chromatin, cell cycle, DNA repair, and immune regulation ► Transcription factors have distinct connections in exhausted versus memory CD8 T cells
Cited by (0)
- 2
Present address: Hofstra North Shore-LIJ School of Medicine, Hempstead, NY 11549, USA
- 3
Present address: Regeneron Pharmaceutical, Tarrytown, NY 10591, USA
Copyright © 2012 Elsevier Inc. All rights reserved.