Molecular Cell
Volume 35, Issue 2, 31 July 2009, Pages 139-140
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MicroRNAs Cross the Line: The Battle for mRNA Stability Enters the Coding Sequence

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A study in this issue of Molecular Cell (Elcheva et al., 2009) shows the inherent instability of the βTrCP1 mRNA to be caused by microRNA-183 targeting the coding sequence; interestingly, this action is directly opposed by the RNA-binding protein CRD-BP.

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