Molecular Cell
Volume 56, Issue 4, 20 November 2014, Pages 469-480
Journal home page for Molecular Cell

Review
The Two Faces of Receptor Interacting Protein Kinase-1

https://doi.org/10.1016/j.molcel.2014.11.001Get rights and content
Under an Elsevier user license
open archive

Receptor Interacting Protein Kinase-1 (RIPK1), a key player in inflammation and cell death, assumes opposite functions depending on the cellular context and its posttranslational modifications. Genetic evidence supported by biochemical and cellular biology approaches sheds light on the circumstances in which RIPK1 promotes or inhibits these processes.

Cited by (0)