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Facilitation of Rat Mammary Tumour Growth by BCG

Abstract

EXPERIMENTAL infections with “bacillus Calmette-Guérin” (BCG) have been shown to enhance the activity of the reticulo-endothelial system (RES)1, to increase the formation of antibody against unrelated bacterial antigens2, to accelerate the rejection of normal tissue homografts3,4 and to enhance host resistance to grafted5–7 or primary induced5,8,9 animal tumours. Experimental leukaemia can be cured10 and remissions in human leukaemia prolonged with BCG treatment11.

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PIESSENS, W., LACHAPELLE, F., LEGROS, N. et al. Facilitation of Rat Mammary Tumour Growth by BCG. Nature 228, 1210–1211 (1970). https://doi.org/10.1038/2281210a0

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