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Systemic inflammation as a confounding factor in cancer biomarker discovery and validation

Nature Reviews Cancer volume 10, pages 2–3 (2010)Cite this article

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Cancer and inflammation are inextricably linked and cancer patients have local and systemic changes in inflammatory parameters. However, this crucial aspect of tumour biology is often overlooked in biomarker studies and needs to be urgently addressed.

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Figure 1: A network of local and systemic inflammation in cancer patients.

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Authors and Affiliations

  1. Department of Immunology, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Roentgena 5, Warsaw, 02-781, Poland

    Magdalena Chechlinska

  2. Department of Molecular Biology, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Roentgena 5, Warsaw, 02-781, Poland

    Magdalena Kowalewska & Radoslawa Nowak

Authors
  1. Magdalena Chechlinska
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  2. Magdalena Kowalewska
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  3. Radoslawa Nowak
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Correspondence to Magdalena Chechlinska.

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Chechlinska, M., Kowalewska, M. & Nowak, R. Systemic inflammation as a confounding factor in cancer biomarker discovery and validation. Nat Rev Cancer 10, 2–3 (2010). https://doi.org/10.1038/nrc2782

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