Sudden onset bilateral sensorineural hearing loss: a manifestation of occult breast carcinoma

J Laryngol Otol. 2001 Nov;115(11):907-10. doi: 10.1258/0022215011909323.

Abstract

Diffuse infiltration of the meninges by metastatic carcinoma (meningeal carcinomastosis) is a potential complication of systemic malignancy. It may present with a variety of neurological symptoms as any aspect of the neuraxis can be affected. Often there is a history of pre-existing malignancy. The authors describe a case with an initial presentation of sudden onset profound bilateral sensorineural hearing loss. The underlying pathology was found to be an occult breast carcinoma, a previously unreported finding. The role of cerebrospinal fluid cytology and radio-imaging in diagnosis is discussed. All previously reported cases of sudden hearing loss and meningeal carcinomatosis are reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / secondary*
  • Breast Neoplasms / complications*
  • Breast Neoplasms / pathology
  • Female
  • Hearing Loss, Sensorineural / etiology*
  • Humans
  • Meningeal Neoplasms / pathology
  • Meningeal Neoplasms / secondary*
  • Middle Aged
  • Neoplasms, Unknown Primary / complications*
  • Neoplasms, Unknown Primary / pathology