Evaluation of cumulative prognostic scores based on the systemic inflammatory response in patients with inoperable non-small-cell lung cancer

Br J Cancer. 2003 Sep 15;89(6):1028-30. doi: 10.1038/sj.bjc.6601242.

Abstract

A score based on the combination of the systemic inflammatory response and albumin hazards ratio (HR) 1.70, 95% CI 1.23 - 2.35, P=0.001) was comparable in prognostic value to that based on stage and performance status (HR 1.48, 95% CI 1.12 - 1.95, P=0.006) in patients with inoperable non-small-cell lung cancer. The former is simple to measure and well standardised.

MeSH terms

  • Adenocarcinoma / blood
  • Adenocarcinoma / diagnosis
  • Albumins / analysis*
  • Biomarkers, Tumor / analysis*
  • C-Reactive Protein / analysis*
  • Carcinoma, Non-Small-Cell Lung / blood
  • Carcinoma, Non-Small-Cell Lung / diagnosis*
  • Carcinoma, Squamous Cell / blood
  • Carcinoma, Squamous Cell / diagnosis
  • Female
  • Humans
  • Hypoalbuminemia / complications
  • Inflammation
  • Karnofsky Performance Status
  • Lung Neoplasms / blood
  • Lung Neoplasms / diagnosis*
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Prognosis
  • Prospective Studies
  • Retrospective Studies

Substances

  • Albumins
  • Biomarkers, Tumor
  • C-Reactive Protein