Recent progress in the battle between oncolytic viruses and tumours

Kelley A Parato; Donna Senger; Peter A J Forsyth; John C Bell

doi:10.1038/nrc1750

Recent progress in the battle between oncolytic viruses and tumours

Nat Rev Cancer. 2005 Dec;5(12):965-76. doi: 10.1038/nrc1750.

Authors

Kelley A Parato¹, Donna Senger, Peter A J Forsyth, John C Bell

Affiliation

¹ Centre for Cancer Therapeutics, Ottawa Health Research Institute, 503 Smyth Road, Ottawa, Ontario, Canada K1H 8L6.

PMID: 16294217
DOI: 10.1038/nrc1750

Abstract

In the past 5 years, the field of oncolytic virus research has matured significantly and is moving past the stage of being a laboratory novelty into a new era of preclinical and clinical trials. What have recent anticancer trials of oncolytic viruses taught us about this exciting new line of therapeutics?

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Clinical Trials as Topic
Genetic Variation
Humans
Linkage Disequilibrium
Neoplasms / therapy*
Neoplasms / virology
Oncolytic Virotherapy*
Oncolytic Viruses / physiology*
Risk Factors