Abstract
This review will focus on the role of nuclear factor kappaB (NF-kappaB) signaling in hematopoietic differentiation. We will also discuss several hematopoietic pathologies associated with deregulation of NF-kappaB and their potential therapies.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Cell Differentiation*
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Dendritic Cells / metabolism
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Dendritic Cells / physiology
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Graft Rejection / metabolism
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Hematologic Diseases / metabolism*
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Hematopoiesis*
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Humans
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Myeloid Cells / metabolism
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NF-kappa B / metabolism*
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Signal Transduction
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T-Lymphocytes / metabolism
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T-Lymphocytes / physiology