Abstract
Cellular and humoral immune parameters were evaluated in a series of brain-tumor patients, 42 with glioblastoma multiforme, 17 with other anaplastic gliomas, and 17 with meningiomas. A degree of anergy was found, which seems in the group as a whole to be proportional to the degree of anaplasia. In addition, serial bimonthyl testing in individual cases revealed further reduction in certain immune responses coincident with clinical decline.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Antibodies, Viral / analysis
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Brain Neoplasms / immunology*
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Brain Neoplasms / therapy
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Glioblastoma / immunology
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Glioma / immunology*
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Glioma / therapy
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Humans
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Hypersensitivity, Delayed
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Immunity*
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Immunity, Cellular*
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Immunoglobulin A / analysis
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Immunoglobulin G / analysis
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Immunoglobulin M / analysis
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Meningioma / immunology*
Substances
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Antibodies, Viral
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Immunoglobulin A
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Immunoglobulin G
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Immunoglobulin M