Releasing the Brakes on Cancer Immunotherapy

N Engl J Med. 2015 Oct 15;373(16):1490-2. doi: 10.1056/NEJMp1510079. Epub 2015 Sep 8.

Author

Affiliation

¹ From the Department of Medicine, Division of Hematology-Oncology, and the Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles.

PMID: 26348216
DOI: 10.1056/NEJMp1510079

No abstract available

MeSH terms

Animals
Antibodies, Monoclonal / therapeutic use*
CTLA-4 Antigen / antagonists & inhibitors*
CTLA-4 Antigen / physiology
Humans
Immunotherapy*
Lymph Nodes / immunology
Lymphocyte Activation / physiology
Neoplasms / immunology
Neoplasms / therapy*
Programmed Cell Death 1 Receptor / antagonists & inhibitors*
T-Lymphocytes / physiology*

Substances

Antibodies, Monoclonal
CTLA-4 Antigen
PDCD1 protein, human
Programmed Cell Death 1 Receptor