Abstract
A new multisystem inflammatory syndrome apparently related to infection with SARS-CoV-2 has recently been reported in older children (known as MIS-C), manifested by severe abdominal pain, cardiac dysfunction and shock. Here, I discuss the similarities and differences between MIS-C and Kawasaki disease, focusing on their epidemiology, aetiology and pathophysiological mechanisms.
Publication types
-
Research Support, N.I.H., Extramural
-
Review
MeSH terms
-
Abdominal Pain / pathology
-
Abdominal Pain / virology
-
Betacoronavirus / pathogenicity*
-
COVID-19
-
Child
-
Coronavirus Infections / pathology*
-
Coronavirus Infections / virology*
-
Heart Diseases / pathology
-
Heart Diseases / virology
-
Humans
-
Inflammation / etiology*
-
Inflammation / pathology*
-
Mucocutaneous Lymph Node Syndrome / pathology
-
Mucocutaneous Lymph Node Syndrome / virology
-
Pandemics
-
Pneumonia, Viral / pathology*
-
Pneumonia, Viral / virology*
-
SARS-CoV-2
-
Shock / pathology
-
Shock / virology
-
Systemic Inflammatory Response Syndrome / pathology*
-
Systemic Inflammatory Response Syndrome / virology*
Supplementary concepts
-
pediatric multisystem inflammatory disease, COVID-19 related