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Engineered T cells directed at tumors with defined allelic loss.
Hamburger AE, DiAndreth B, Cui J, Daris ME, Munguia ML, Deshmukh K, Mock JY, Asuelime GE, Lim ED, Kreke MR, Tokatlian T, Kamb A. Hamburger AE, et al. Among authors: asuelime ge. Mol Immunol. 2020 Dec;128:298-310. doi: 10.1016/j.molimm.2020.09.012. Epub 2020 Oct 1. Mol Immunol. 2020. PMID: 33012527 Free article.
Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells.
Tokatlian T, Asuelime GE, Mock JY, DiAndreth B, Sharma S, Toledo Warshaviak D, Daris ME, Bolanos K, Luna BL, Naradikian MS, Deshmukh K, Hamburger AE, Kamb A. Tokatlian T, et al. Among authors: asuelime ge. J Immunother Cancer. 2022 Jan;10(1):e003826. doi: 10.1136/jitc-2021-003826. J Immunother Cancer. 2022. PMID: 35091455 Free PMC article.
Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity.
Tokatlian T, Asuelime GE, Naradikian MS, Mock JY, Daris ME, Martin AD, Toledo Warshaviak D, Kamb A, Hamburger AE. Tokatlian T, et al. Among authors: asuelime ge. Cancer Res Commun. 2022 Jan 28;2(1):58-65. doi: 10.1158/2767-9764.CRC-21-0165. eCollection 2022 Jan. Cancer Res Commun. 2022. PMID: 36860694 Free PMC article.
Activated Natural Killer Cells in Combination with Anti-GD2 Antibody Dinutuximab Improve Survival of Mice after Surgical Resection of Primary Neuroblastoma.
Barry WE, Jackson JR, Asuelime GE, Wu HW, Sun J, Wan Z, Malvar J, Sheard MA, Wang L, Seeger RC, Kim ES. Barry WE, et al. Among authors: asuelime ge. Clin Cancer Res. 2019 Jan 1;25(1):325-333. doi: 10.1158/1078-0432.CCR-18-1317. Epub 2018 Sep 19. Clin Cancer Res. 2019. PMID: 30232225 Free PMC article.