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Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation.
Sorrentino A, Menevse AN, Michels T, Volpin V, Durst FC, Sax J, Xydia M, Hussein A, Stamova S, Spoerl S, Heuschneider N, Muehlbauer J, Jeltsch KM, Rathinasamy A, Werner-Klein M, Breinig M, Mikietyn D, Kohler C, Poschke I, Purr S, Reidell O, Martins Freire C, Offringa R, Gebhard C, Spang R, Rehli M, Boutros M, Schmidl C, Khandelwal N, Beckhove P. Sorrentino A, et al. Among authors: durst fc. J Immunother Cancer. 2022 May;10(5):e004258. doi: 10.1136/jitc-2021-004258. J Immunother Cancer. 2022. PMID: 35606086 Free PMC article.
TSPO acts as an immune resistance gene involved in the T cell mediated immune control of glioblastoma.
Menevse AN, Ammer LM, Vollmann-Zwerenz A, Kupczyk M, Lorenz J, Weidner L, Hussein A, Sax J, Mühlbauer J, Heuschneider N, Rohrmus C, Mai LS, Jachnik B, Stamova S, Volpin V, Durst FC, Sorrentino A, Xydia M, Milenkovic VM, Bader S, Braun FK, Wetzel C, Albert NL, Tonn JC, Bartenstein P, Proescholdt M, Schmidt NO, Linker RA, Riemenschneider MJ, Beckhove P, Hau P. Menevse AN, et al. Among authors: durst fc. Acta Neuropathol Commun. 2023 May 8;11(1):75. doi: 10.1186/s40478-023-01550-9. Acta Neuropathol Commun. 2023. PMID: 37158962 Free PMC article.
M1 Macrophages Induce Protumor Inflammation in Melanoma Cells through TNFR-NF-κB Signaling.
Kainulainen K, Takabe P, Heikkinen S, Aaltonen N, de la Motte C, Rauhala L, Durst FC, Oikari S, Hukkanen T, Rahunen E, Ikonen E, Hartikainen JM, Ketola K, Pasonen-Seppänen S. Kainulainen K, et al. Among authors: durst fc. J Invest Dermatol. 2022 Nov;142(11):3041-3051.e10. doi: 10.1016/j.jid.2022.04.024. Epub 2022 May 14. J Invest Dermatol. 2022. PMID: 35580697 Free article.