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Year Number of Results
2005 3
2006 2
2007 1
2008 1
2010 1
2015 1
2020 1
2021 1
2022 1
2023 2
2024 0

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Page 1
Preclinical Characterization and Phase I Trial Results of INBRX-109, A Third-Generation, Recombinant, Humanized, Death Receptor 5 Agonist Antibody, in Chondrosarcoma.
Subbiah V, Chawla SP, Conley AP, Wilky BA, Tolcher A, Lakhani NJ, Berz D, Andrianov V, Crago W, Holcomb M, Hussain A, Veldstra C, Kalabus J, O'Neill B, Senne L, Rowell E, Heidt AB, Willis KM, Eckelman BP. Subbiah V, et al. Among authors: eckelman bp. Clin Cancer Res. 2023 Aug 15;29(16):2988-3003. doi: 10.1158/1078-0432.CCR-23-0974. Clin Cancer Res. 2023. PMID: 37265425 Free PMC article. Clinical Trial.
Modulation of CD47-SIRPα innate immune checkpoint axis with Fc-function detuned anti-CD47 therapeutic antibody.
Narla RK, Modi H, Bauer D, Abbasian M, Leisten J, Piccotti JR, Kopytek S, Eckelman BP, Deveraux Q, Timmer J, Zhu D, Wong L, Escoubet L, Raymon HK, Hariharan K. Narla RK, et al. Among authors: eckelman bp. Cancer Immunol Immunother. 2022 Feb;71(2):473-489. doi: 10.1007/s00262-021-03010-6. Epub 2021 Jul 10. Cancer Immunol Immunother. 2022. PMID: 34247273
INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses.
Sulzmaier FJ, Kern N, Ahn SJ, Polovina A, Ho J, Hussain A, Cyprus G, Macedo C, Pandit R, Crago W, Rowell E, Timmer JC, Eckelman BP. Sulzmaier FJ, et al. Among authors: eckelman bp. J Immunother Cancer. 2023 Jan;11(1):e006116. doi: 10.1136/jitc-2022-006116. J Immunother Cancer. 2023. PMID: 36653071 Free PMC article.
Transnitrosylation of XIAP regulates caspase-dependent neuronal cell death.
Nakamura T, Wang L, Wong CC, Scott FL, Eckelman BP, Han X, Tzitzilonis C, Meng F, Gu Z, Holland EA, Clemente AT, Okamoto S, Salvesen GS, Riek R, Yates JR 3rd, Lipton SA. Nakamura T, et al. Among authors: eckelman bp. Mol Cell. 2010 Jul 30;39(2):184-95. doi: 10.1016/j.molcel.2010.07.002. Mol Cell. 2010. PMID: 20670888 Free PMC article.
12 results