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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1979 1
1980 3
1981 1
1983 1
1984 3
1985 4
1986 2
1987 5
1988 3
1989 3
1990 4
1991 11
1992 12
1993 12
1994 13
1995 11
1996 6
1997 7
1998 4
1999 6
2000 2
2001 1
2002 1
2003 6
2004 6
2005 6
2006 5
2007 9
2008 5
2009 17
2010 16
2011 9
2012 20
2013 15
2014 14
2015 8
2016 11
2017 10
2018 5
2019 8
2020 14
2021 12
2022 9
2023 9
2024 3

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Search Results

313 results

Results by year

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Page 1
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα.
Hanan EJ, Braun MG, Heald RA, MacLeod C, Chan C, Clausen S, Edgar KA, Eigenbrot C, Elliott R, Endres N, Friedman LS, Gogol E, Gu XH, Thibodeau RH, Jackson PS, Kiefer JR, Knight JD, Nannini M, Narukulla R, Pace A, Pang J, Purkey HE, Salphati L, Sampath D, Schmidt S, Sideris S, Song K, Sujatha-Bhaskar S, Ultsch M, Wallweber H, Xin J, Yeap S, Young A, Zhong Y, Staben ST. Hanan EJ, et al. Among authors: friedman ls. J Med Chem. 2022 Dec 22;65(24):16589-16621. doi: 10.1021/acs.jmedchem.2c01422. Epub 2022 Dec 1. J Med Chem. 2022. PMID: 36455032
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.
Vasan N, Razavi P, Johnson JL, Shao H, Shah H, Antoine A, Ladewig E, Gorelick A, Lin TY, Toska E, Xu G, Kazmi A, Chang MT, Taylor BS, Dickler MN, Jhaveri K, Chandarlapaty S, Rabadan R, Reznik E, Smith ML, Sebra R, Schimmoller F, Wilson TR, Friedman LS, Cantley LC, Scaltriti M, Baselga J. Vasan N, et al. Among authors: friedman ls. Science. 2019 Nov 8;366(6466):714-723. doi: 10.1126/science.aaw9032. Science. 2019. PMID: 31699932 Free PMC article.
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) Efficacy.
Song KW, Edgar KA, Hanan EJ, Hafner M, Oeh J, Merchant M, Sampath D, Nannini MA, Hong R, Phu L, Forrest WF, Stawiski E, Schmidt S, Endres N, Guan J, Wallin JJ, Cheong J, Plise EG, Lewis Phillips GD, Salphati L, Heffron TP, Olivero AG, Malek S, Staben ST, Kirkpatrick DS, Dey A, Friedman LS. Song KW, et al. Among authors: friedman ls. Cancer Discov. 2022 Jan;12(1):204-219. doi: 10.1158/2159-8290.CD-21-0072. Epub 2021 Sep 20. Cancer Discov. 2022. PMID: 34544753 Free PMC article.
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
Guan J, Zhou W, Hafner M, Blake RA, Chalouni C, Chen IP, De Bruyn T, Giltnane JM, Hartman SJ, Heidersbach A, Houtman R, Ingalla E, Kategaya L, Kleinheinz T, Li J, Martin SE, Modrusan Z, Nannini M, Oeh J, Ubhayakar S, Wang X, Wertz IE, Young A, Yu M, Sampath D, Hager JH, Friedman LS, Daemen A, Metcalfe C. Guan J, et al. Among authors: friedman ls. Cell. 2019 Aug 8;178(4):949-963.e18. doi: 10.1016/j.cell.2019.06.026. Epub 2019 Jul 25. Cell. 2019. PMID: 31353221 Free article.
Delta agent hepatitis.
Chatzinoff M, Friedman LS. Chatzinoff M, et al. Among authors: friedman ls. Infect Dis Clin North Am. 1987 Sep;1(3):529-45. Infect Dis Clin North Am. 1987. PMID: 3332883 Review.
Treatment of Dyslipidemia in Common Liver Diseases.
Speliotes EK, Balakrishnan M, Friedman LS, Corey KE. Speliotes EK, et al. Among authors: friedman ls. Clin Gastroenterol Hepatol. 2018 Aug;16(8):1189-1196. doi: 10.1016/j.cgh.2018.04.023. Epub 2018 Apr 21. Clin Gastroenterol Hepatol. 2018. PMID: 29684459 Free PMC article. Review. No abstract available.
Systemic causes of cholestasis.
Delemos AS, Friedman LS. Delemos AS, et al. Among authors: friedman ls. Clin Liver Dis. 2013 May;17(2):301-17. doi: 10.1016/j.cld.2012.11.001. Epub 2013 Jan 26. Clin Liver Dis. 2013. PMID: 23540504 Free PMC article. Review.
Liver transplantation.
Muñoz SJ, Friedman LS. Muñoz SJ, et al. Among authors: friedman ls. Med Clin North Am. 1989 Jul;73(4):1011-39. doi: 10.1016/s0025-7125(16)30651-4. Med Clin North Am. 1989. PMID: 2657259 Free article. Review.
Introduction of Clinical Practice Update Committee Articles.
Friedman LS, Inadomi JM, Kalloo AM, Katzka DA, Kim LS, Koch J, Lieberman D, Lichtenstein GR, Lim JK, Pandolfino JE, Shin AS, Siedler MR. Friedman LS, et al. Clin Gastroenterol Hepatol. 2017 Jan;15(1):4. doi: 10.1016/j.cgh.2016.11.011. Clin Gastroenterol Hepatol. 2017. PMID: 27979048 No abstract available.
Pharmacotherapy for Friedreich ataxia.
Tsou AY, Friedman LS, Wilson RB, Lynch DR. Tsou AY, et al. Among authors: friedman ls. CNS Drugs. 2009;23(3):213-23. doi: 10.2165/00023210-200923030-00003. CNS Drugs. 2009. PMID: 19320530 Review.
313 results