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Page 1
Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy.
Hanoteau A, Newton JM, Krupar R, Huang C, Liu HC, Gaspero A, Gartrell RD, Saenger YM, Hart TD, Santegoets SJ, Laoui D, Spanos C, Parikh F, Jayaraman P, Zhang B, Van der Burg SH, Van Ginderachter JA, Melief CJM, Sikora AG. Hanoteau A, et al. J Immunother Cancer. 2019 Jan 15;7(1):10. doi: 10.1186/s40425-018-0485-9. J Immunother Cancer. 2019. PMID: 30646957 Free PMC article.
Immune microenvironment modulation unmasks therapeutic benefit of radiotherapy and checkpoint inhibition.
Newton JM, Hanoteau A, Liu HC, Gaspero A, Parikh F, Gartrell-Corrado RD, Hart TD, Laoui D, Van Ginderachter JA, Dharmaraj N, Spanos WC, Saenger Y, Young S, Sikora AG. Newton JM, et al. Among authors: hanoteau a. J Immunother Cancer. 2019 Aug 13;7(1):216. doi: 10.1186/s40425-019-0698-6. J Immunother Cancer. 2019. PMID: 31409394 Free PMC article. Clinical Trial.
Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape.
Dharmaraj N, Piotrowski SL, Huang C, Newton JM, Golfman LS, Hanoteau A, Koshy ST, Li AW, Pulikkathara MX, Zhang B, Burks JK, Mooney DJ, Lei YL, Sikora AG, Young S. Dharmaraj N, et al. Among authors: hanoteau a. Oncoimmunology. 2019 Feb 6;8(4):e1568809. doi: 10.1080/2162402X.2019.1568809. eCollection 2019. Oncoimmunology. 2019. PMID: 30906661 Free PMC article.
TGF-β1 programmed myeloid-derived suppressor cells (MDSC) acquire immune-stimulating and tumor killing activity capable of rejecting established tumors in combination with radiotherapy.
Jayaraman P, Parikh F, Newton JM, Hanoteau A, Rivas C, Krupar R, Rajapakshe K, Pathak R, Kanthaswamy K, MacLaren C, Huang S, Coarfa C, Spanos C, Edwards DP, Parihar R, Sikora AG. Jayaraman P, et al. Among authors: hanoteau a. Oncoimmunology. 2018 Jul 26;7(10):e1490853. doi: 10.1080/2162402X.2018.1490853. eCollection 2018. Oncoimmunology. 2018. PMID: 30288358 Free PMC article.
Cyclophosphamide treatment induces rejection of established P815 mastocytoma by enhancing CD4 priming and intratumoral infiltration of P1E/H-2K(d) -specific CD8+ T cells.
Rahir G, Wathelet N, Hanoteau A, Henin C, Oldenhove G, Galuppo A, Lanaya H, Colau D, Mackay CR, Van den Eynde B, Moser M. Rahir G, et al. Among authors: hanoteau a. Int J Cancer. 2014 Jun 15;134(12):2841-52. doi: 10.1002/ijc.28617. Epub 2013 Nov 29. Int J Cancer. 2014. PMID: 24249003 Free article.